Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | PDE6A | P16499 | 1/20 | 0.39 |
| ▸ | PDE6G | P18545 | 1/20 | 0.39 |
| ▸ | PDE6B | P35913 | 1/20 | 0.39 |
| ▸ | PDE6C | P51160 | 1/20 | 0.39 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25205149 | 1.00 | NR3C1 (0.47) | NR3C1L3MBTL1GRIN1GRIN2BALDH1A1 | |
| SCHEMBL25560840 | 0.85 | GRIN2B (0.49) | NR3C1GRIN1GRIN2BALDH1A1PKM | |
| SCHEMBL30328294 | 0.79 | ALDH1A1 (0.43) | NR3C1ALDH1A1PTGDR2 | |
| SCHEMBL5794517 | 0.76 | L3MBTL1 (0.54) | NR3C1L3MBTL1ALDH1A1 | |
| SCHEMBL25234793 | 0.75 | GRIN2B (0.54) | NR3C1GRIN1GRIN2BALDH1A1PKM | |
| SCHEMBL31001106 | 0.73 | IGF1R (0.51) | NR3C1L3MBTL1GRIN1GRIN2BTLR7 | |
| SCHEMBL25560931 | 0.71 | GRIN1 (0.46) | NR3C1GRIN1GRIN2BPDE5ATLR7 | |
| SCHEMBL17949620 | 0.71 | ALDH1A1 (0.54) | L3MBTL1GRIN1GRIN2BALDH1A1PKM | |
| SCHEMBL30328542 | 0.70 | PDE10A (0.34) | GRIN1GRIN2BALDH1A1 | |
| SCHEMBL17963113 | 0.70 | NR3C1 (0.72) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4363423-A1 | CDK2 INHIBITORS | Blueprint Medicines Corporation (US) | 2024-05-08 | — | — | EP | disclosed |
| WO-2023278326-A1 | CDK2 INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-01-05 | — | — | WO | disclosed |