SCHEMBL3031749

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3031755	1.00	ALOX15 (0.37)	ALOX15LMNACYP1A2CYP2D6HTT
	SCHEMBL1277666	0.89	EZH2 (0.34)	ALOX15SMN1; SMN2ALDH1A1KDM4EHPGD
	SCHEMBL1277669	0.89	EZH2 (0.34)	ALOX15SMN1; SMN2ALDH1A1KDM4EHPGD
	SCHEMBL27964855	0.88	ALOX15 (0.38)	ALOX15LMNACYP1A2CYP2D6HTT
	SCHEMBL1277208	0.84	—	—
	SCHEMBL1277938	0.83	P2RX3 (0.33)	ALOX15ALDH1A1HPGD
	SCHEMBL1277940	0.83	P2RX3 (0.33)	ALOX15ALDH1A1HPGD
	SCHEMBL1277598	0.83	KDM4E (0.32)	ALOX15ALDH1A1KDM4E
	SCHEMBL1277602	0.83	KDM4E (0.32)	ALOX15ALDH1A1KDM4E
	SCHEMBL1277590	0.83	TDO2 (0.31)	ALOX15ALDH1A1CA1CA2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.