SCHEMBL30317567

SCHEMBL30317567

CC(C)[C@H](NC(=O)CNC(=O)COC(C)(C)C)C(=O)N[C@@H](CCCNC(N)=O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ C3AR1 Q16581 1/20 0.42
▸ FURIN P09958 10/20 0.39
▸ PRSS1 P07477 2/20 0.37
▸ CTDSP1 Q9GZU7 1/20 0.34
▸ NOD1 Q9Y239 1/20 0.33
▸ SHMT1 P34896 1/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ FOLH1 Q04609 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ KLK7 P49862 1/20 0.33
▸ CTSS P25774 1/20 0.32
▸ CTSK P43235 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23629902 0.87 MEN1 (0.44) C3AR1FURINPRSS1MEN1KMT2A
SCHEMBL24191073 0.85 C3AR1 (0.42) C3AR1FURINPRSS1CTDSP1NOD1
SCHEMBL30317564 0.85 C3AR1 (0.42) C3AR1FURINPRSS1CTDSP1NOD1
SCHEMBL31319761 0.84 C3AR1 (0.41) C3AR1FURINPRSS1CTDSP1NOD1
SCHEMBL29620243 0.84 C3AR1 (0.42) C3AR1FURINPRSS1CTDSP1NOD1
Trifluoroacetic Acid SCHEMBL23630136 0.82 QRFPR (0.39) C3AR1FURINPRSS1CTDSP1SHMT1
SCHEMBL30317553 0.81 C3AR1 (0.41) C3AR1FURINNOD1MEN1KMT2A
SCHEMBL17581833 0.81 CTSS (0.52) C3AR1MEN1KMT2AGAACTSS
SCHEMBL12283739 0.81 CTSS (0.52) C3AR1MEN1KMT2AGAACTSS
SCHEMBL13436631 0.81 CTSS (0.52) C3AR1MEN1KMT2AGAACTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250115546-A1 LINKERS FOR ANTIBODY DRUG CONJUGATES UNIV TEXAS (US) 2025-04-10 — — US disclosed
CN-111065623-B9 Linker for antibody drug conjugates 德克萨斯州大学系统董事会 2024-10-25 — — CN disclosed
CN-118652192-A Linker for antibody drug conjugates 德克萨斯州大学系统董事会 2024-09-17 — — CN disclosed
US-12084403-B2 Linkers for antibody drug conjugates THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-09-10 — — US disclosed
CN-111065623-B Linker for antibody drug conjugates 德克萨斯州大学系统董事会 2024-09-03 — — CN disclosed
US-20240059647-A1 LINKERS FOR ANTIBODY DRUG CONJUGATES UNIV TEXAS (US) 2024-02-22 — — US disclosed
US-11629122-B2 Linkers for antibody drug conjugates THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-04-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115546-A1 LINKERS FOR ANTIBODY DRUG CONJUGATES CD47, EPCAM, SDCBP C3AR1 1357/4885FURIN 572/4885PRSS1 4421/4885
US-12084403-B2 Linkers for antibody drug conjugates CD47, EPCAM, SDCBP C3AR1 1357/4885FURIN 572/4885PRSS1 4421/4885
US-20240059647-A1 LINKERS FOR ANTIBODY DRUG CONJUGATES CD47, EPCAM, SDCBP C3AR1 1357/4885FURIN 572/4885PRSS1 4421/4885
US-11629122-B2 Linkers for antibody drug conjugates CD47, EPCAM, FCGRT C3AR1 1121/4885FURIN 570/4885PRSS1 4454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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