⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031840 | 0.70 | NOX1 (0.31) | — | |
| SCHEMBL3035317 | 0.67 | NOX1 (0.43) | — | |
| SCHEMBL16848275 | 0.67 | MEN1 (0.34) | — | |
| SCHEMBL10476547 | 0.64 | TERT (0.39) | — | |
| SCHEMBL11892669 | 0.62 | CRHR1 (0.35) | — | |
| SCHEMBL2434660 | 0.62 | MAPT (0.35) | — | |
| SCHEMBL11892660 | 0.60 | TP53 (0.38) | — | |
| SCHEMBL3035959 | 0.60 | MAPT (0.36) | — | |
| SCHEMBL17183625 | 0.59 | NOX1 (0.44) | — | |
| SCHEMBL3026252 | 0.59 | NOX1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9067900-B2 | Diaminophenothiazine compounds, a method for preparing same and uses thereof | PHARMA HYDRO DEVELOPMENT—P.H.D. (FR) | 2015-06-30 | — | — | US | disclosed |
| EP-2185531-B1 | Diaminophenothiazine compounds, a method for preparing same and uses thereof | PHARMA HYDRO DEV P H D (FR) | 2012-07-25 | — | — | EP | disclosed |
| US-20100204215-A1 | NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF | PHARMA HYDRO DEVELOPMENT - P.H.D. (FR) | 2010-08-12 | — | — | US | disclosed |
| EP-2185531-A2 | NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF | Pharma Hydro Development - P.H.D. (FR) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009044054-A2 | NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF | PHARMA HYDRO DEVELOPMENT - P.H.D. (FR) | 2009-04-09 | — | — | WO | disclosed |