Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30319370 | 0.82 | TSHR (0.42) | KMT2APOLBSMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL30319390 | 0.76 | KMT2A (0.44) | KMT2APOLBSMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL24077389 | 0.75 | ATM (0.44) | KMT2APOLBSMN1; SMN2MEN1PARP1 | |
| SCHEMBL30319401 | 0.75 | KDM4E (0.63) | KMT2APOLBSMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL13995824 | 0.75 | KDM4E (0.63) | KMT2APOLBSMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL30319337 | 0.74 | AR (0.41) | KMT2APOLBSMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL30319413 | 0.74 | POLB (0.47) | KMT2APOLBSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL29874776 | 0.68 | TSHR (0.39) | KMT2APOLBSMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL29875213 | 0.68 | TSHR (0.39) | KMT2APOLBSMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL14240098 | 0.68 | CTNNB1 (0.40) | POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161905-A1 | SUBSTITUTED (PHTHALAZIN-1-YLMETHYL)UREAS, SUBSTITUTED N-(PHTHALAZIN-1-YLMETHYL)AMIDES, AND ANALOGUES THEREOF | Arbutus Biopharma Corporation (CA) | 2023-04-12 | — | — | EP | disclosed |