Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 13/20 | 0.74 |
| ▸ | GSK3B | P49841 | 13/20 | 0.74 |
| ▸ | CDK5 | Q00535 | 11/20 | 0.67 |
| ▸ | CDK5R1 | Q15078 | 11/20 | 0.67 |
| ▸ | CDK1 | P06493 | 7/20 | 0.67 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.67 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.67 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.67 |
| ▸ | CDK2 | P24941 | 3/20 | 0.67 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.67 |
| ▸ | CDK4 | P11802 | 2/20 | 0.67 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.67 |
| ▸ | CCND1 | P24385 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | CDK14 | O94921 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | SRC | P12931 | 1/20 | 0.67 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.67 |
| ▸ | CDK11B | P21127 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30319805 | 0.86 | GSK3A (0.76) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30319763 | 0.85 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30319777 | 0.85 | GSK3A (0.74) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL29421607 | 0.80 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30597674 | 0.77 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30319773 | 0.73 | CDK2 (0.51) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30380971 | 0.72 | GSK3A (0.70) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30597679 | 0.72 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL30273058 | 0.72 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 | |
| SCHEMBL23064865 | 0.69 | CDK2 (1.00) | GSK3AGSK3BCDK5CDK5R1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115969814-A | Novel pharmaceutical formulations containing indirubin and derivatives thereof and methods of making and using the same | 法斯瑞斯公司 | 2023-04-18 | — | — | CN | disclosed |