Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 11/20 | 0.71 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24155083 | 0.86 | MAT2A (0.71) | MAT2AMAPK14DHODHMAPK13MAPK12 | |
| SCHEMBL24110060 | 0.83 | MAT2A (1.00) | MAT2A | |
| SCHEMBL25304498 | 0.83 | MAT2A (0.70) | MAT2AMAPK14DHODHMAPK13MAPK12 | |
| SCHEMBL25305158 | 0.76 | MAT2A (0.58) | MAT2AMAPK14DHODHMAPK13MAPK12 | |
| SCHEMBL30283151 | 0.76 | MAT2A (0.58) | MAT2AMAPK14DHODHMAPK13MAPK12 | |
| SCHEMBL25305119 | 0.76 | MAT2A (0.58) | MAT2AMAPK14DHODHMAPK13MAPK12 | |
| SCHEMBL24109648 | 0.72 | MAT2A (0.80) | MAT2A | |
| SCHEMBL28889151 | 0.71 | MAT2A (0.79) | MAT2A | |
| SCHEMBL24110092 | 0.71 | MAT2A (0.78) | MAT2A | |
| SCHEMBL25256984 | 0.71 | MAT2A (0.54) | MAT2AGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867541-A | Aminopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-03-28 | — | — | CN | disclosed |