Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3032024

CC(O)COCC(O)C[N+](C)(C)C.[Cl-]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 2/20 0.35
CHRM1 known ✓ P11229 2/20 0.35
CHRM3 known ✓ P20309 1/20 0.34
SLC6A2 known ✓ P23975 1/20 0.31
SLC6A3 known ✓ Q01959 1/20 0.31
HSD17B10 Q99714 1/20 0.50
MAPT P10636 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.39
GALR3 O60755 1/20 0.39
BLM P54132 1/20 0.39
LMNA P02545 4/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 1/20 0.37
SLC22A16 Q86VW1 1/20 0.37
MAPK1 P28482 1/20 0.36
TSHR P16473 2/20 0.35
CHRM4 P08173 2/20 0.35
TBXA2R P21731 1/20 0.35
CHRM5 P08912 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2341008 1.00 HSD17B10 (0.50) HSD17B10MAPTSMN1; SMN2GALR3BLM
SCHEMBL3833772 0.98 HSD17B10 (0.52) HSD17B10MAPTSMN1; SMN2GALR3BLM
Hydrochloric Acid SCHEMBL2341007 0.95 HSD17B10 (0.50) HSD17B10MAPTSMN1; SMN2GALR3BLM
Hydrochloric Acid SCHEMBL146731 0.90 MAPT (0.48) HSD17B10MAPTSMN1; SMN2GALR3BLM
SCHEMBL1131168 0.87 MAPT (0.44) HSD17B10MAPTSMN1; SMN2GALR3BLM
Hydrochloric Acid SCHEMBL2341005 0.86 TDP1 (0.48) HSD17B10MAPTSMN1; SMN2GALR3BLM
Hydrochloric Acid SCHEMBL347524 0.85 MAPT (0.42) HSD17B10MAPTSMN1; SMN2GALR3BLM
SCHEMBL23560611 0.82 HSD17B10 (0.62) HSD17B10MAPTLMNATDP1KDM4E
SCHEMBL30368919 0.82 HSD17B10 (0.60) HSD17B10MAPTLMNATDP1KDM4E
Hydrochloric Acid SCHEMBL30298374 0.80 MAPT (0.44) HSD17B10MAPTSMN1; SMN2GALR3BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3488899-B1 HAIR CARE COMPOSITION LAMBERTI SPA (IT) 2021-08-11 EP disclosed
US-10993900-B2 Cosmetic and household care compositions LAMBERTI SPA (IT) 2021-05-04 US disclosed
US-20200069554-A1 COSMETIC AND HOUSEHOLD CARE COMPOSITIONS LAMBERTI SPA (IT) 2020-03-05 US disclosed
US-10441524-B2 Cosmetic and household care composition LAMBERTI SPA (IT) 2019-10-15 US disclosed
EP-3488899-A1 HAIR CARE COMPOSITION Lamberti SPA (IT) 2019-05-29 EP disclosed
EP-3041585-B1 COSMETIC AND HOUSEHOLD CARE COMPOSITIONS LAMBERTI SPA (IT) 2019-01-02 EP disclosed
EP-2398885-B1 PERSONAL CLEANSING COMPOSITION INCLUDING A STRUCTURED SURFACTANT SYSTEM AND A SUN PROTECTION FACTOR COMPOSITION DIAL CORP (US) 2016-12-28 EP disclosed
US-20160193134-A1 COSMETIC AND HOUSEHOLD CARE COMPOSITIONS LAMBERTI SPA (IT) 2016-07-07 US disclosed
US-20100209363-A1 PERSONAL CLEANSING COMPOSITION INCLUDING A STRUCTURED SURFACTANT SYSTEM AND A SUN PROTECTION FACTOR COMPOSITION THE DIAL CORPORATION (US) 2010-08-19 US disclosed
EP-1517709-B1 TRANSDERMAL DRUG DELIVERY SYSTEM SINTOV AMNON (IL) 2008-06-11 EP disclosed
US-20050226910-A1 Transdermal drug delivery system AMNON SINTOV (IL) 2005-10-13 US disclosed
EP-1517709-A1 TRANSDERMAL DRUG DELIVERY SYSTEM Sintov, Amnon (IL) 2005-03-30 EP disclosed
WO-2004000358-A1 TRANSDERMAL DRUG DELIVERY SYSTEM SINTOV AMNON (IL) 2003-12-31 WO disclosed