SCHEMBL3833772

SCHEMBL3833772

CC(O)COCC(O)C[N+](C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 2/20 0.39
MAPT P10636 3/20 0.38
KDM4E B2RXH2 1/20 0.38
SLC22A16 Q86VW1 1/20 0.38
MAPK1 P28482 1/20 0.37
TSHR P16473 3/20 0.37
CHRM2 P08172 2/20 0.37
CHRM4 P08173 2/20 0.37
CHRM1 P11229 2/20 0.37
TBXA2R P21731 1/20 0.37
LMNA P02545 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CHRM5 P08912 1/20 0.35
CHRM3 P20309 1/20 0.35
CYP2C9 P11712 1/20 0.35
GALR3 O60755 1/20 0.35
BLM P54132 1/20 0.35
FYN P06241 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2341007 0.98 HSD17B10 (0.50) HSD17B10TDP1MAPTKDM4ESLC22A16
Hydrochloric Acid SCHEMBL3032024 0.98 HSD17B10 (0.50) HSD17B10TDP1MAPTKDM4ESLC22A16
Hydrochloric Acid SCHEMBL2341008 0.98 HSD17B10 (0.50) HSD17B10TDP1MAPTKDM4ESLC22A16
SCHEMBL1131168 0.89 MAPT (0.44) HSD17B10MAPTKDM4ESLC22A16TSHR
Hydrochloric Acid SCHEMBL347524 0.87 MAPT (0.42) HSD17B10MAPTKDM4ESLC22A16TSHR
Hydrochloric Acid SCHEMBL146731 0.87 MAPT (0.48) HSD17B10MAPTKDM4ESLC22A16TSHR
SCHEMBL23560611 0.84 HSD17B10 (0.62) HSD17B10TDP1MAPTKDM4EMAPK1
SCHEMBL30368919 0.84 HSD17B10 (0.60) HSD17B10TDP1MAPTKDM4EMAPK1
Hydrochloric Acid SCHEMBL2341005 0.83 TDP1 (0.48) HSD17B10TDP1MAPTSLC22A16MAPK1
SCHEMBL5524685 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1585496-B1 COSMETIC COMPOSITION COMPRISING QUATERNIZED LANOLIN COLGATE PALMOLIVE CO (US) 2009-09-16 EP claimed
EP-3137270-B1 WOOD PRESERVATIVE COMPOSITION ARCH WOOD PROTECTION INC (US) 2024-02-21 EP disclosed
EP-4234633-A2 WOOD PRESERVATIVE COMPOSITION Arch Wood Protection, Inc. (US) 2023-08-30 EP disclosed
US-11312038-B2 Wood preservative composition ARCH WOOD PROTECTION, INC. (US) 2022-04-26 US disclosed
US-11134675-B2 Methods and compositions for delivery of polynucleotides MONSANTO TECHNOLOGY LLC (US) 2021-10-05 US disclosed
EP-3389673-B1 METHODS AND COMPOSITIONS FOR DELIVERY OF POLYNUCLEOTIDES MONSANTO TECHNOLOGY LLC (US) 2021-02-17 EP disclosed
US-20180360030-A1 METHODS AND COMPOSITIONS FOR DELIVERY OF POLYNUCLEOTIDES MONSANTO TECHNOLOGY LLC 2018-12-20 US disclosed
EP-3389673-A1 METHODS AND COMPOSITIONS FOR DELIVERY OF POLYNUCLEOTIDES Monsanto Technology LLC (US) 2018-10-24 EP disclosed
US-9961895-B2 Additives for use in wood preservation ARCH TIMBER PROTECTION LIMITED (GB) 2018-05-08 US disclosed
US-20170251661-A1 ADDITIVES FOR USE IN WOOD PRESERVATION ARCH WOOD PROTECTION, INC. 2017-09-07 US disclosed
WO-2017106339-A1 METHODS AND COMPOSITIONS FOR DELIVERY OF POLYNUCLEOTIDES MONSANTO TECHNOLOGY LLC (US) 2017-06-22 WO disclosed
US-9603358-B2 Additives for use in wood preservation ARCH TIMBER PROTECTION LIMITED (GB) 2017-03-28 US disclosed
EP-3137270-A1 WOOD PRESERVATIVE COMPOSITION Arch Wood Protection, Inc. (US) 2017-03-08 EP disclosed
US-20160286793-A1 ADDITIVES FOR USE IN WOOD PRESERVATION ARCH WOOD PROTECTION, INC. 2016-10-06 US disclosed
US-20150314471-A1 WOOD PRESERVATIVE COMPOSITION ARCH WOOD PROTECTION, INC. 2015-11-05 US disclosed
WO-2015168456-A1 WOOD PRESERVATIVE COMPOSITION ARCH WOOD PROTECTION, INC. (US) 2015-11-05 WO disclosed
US-20140242404-A1 ADDITIVES FOR USE IN WOOD PRESERVATION ARCH TIMBER PROTECTION LIMITED (GB) 2014-08-28 US disclosed
US-6455058-B1 ANTIDANDRUFF AGENT SUCH AS SALICYLIC ACID, (2) A POLYETHYLENIMINE, AND (3) AN AMPHOTERIC SURFACTANT. THE COMPOSITION PROVIDES SUPERIOR EFFECTS FOR REPAIRING DAMAGED HAIR, PROTECTING HAIR AGAINST CHEMICAL AND MECHANICAL DAMAGE AMITEE COSMETICS, INC. 2002-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140242404-A1 ADDITIVES FOR USE IN WOOD PRESERVATION CMA1, DDC, AOC1 HSD17B10 1445/4885TDP1 1461/4885MAPT 1194/4885
US-20150314471-A1 WOOD PRESERVATIVE COMPOSITION MGAM, AGL, GANAB HSD17B10 575/4885TDP1 159/4885MAPT 1387/4885
US-20160286793-A1 ADDITIVES FOR USE IN WOOD PRESERVATION CMA1, DDC, AOC1 HSD17B10 1445/4885TDP1 1461/4885MAPT 1194/4885
US-20170251661-A1 ADDITIVES FOR USE IN WOOD PRESERVATION CMA1, DDC, AOC1 HSD17B10 1445/4885TDP1 1461/4885MAPT 1194/4885
US-11312038-B2 Wood preservative composition MGAM, AGL, GANAB HSD17B10 575/4885TDP1 159/4885MAPT 1387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.