Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131168 | 0.97 | MAPT (0.44) | MAPTKDM4ESLC22A16SMN1; SMN2GALR3 | |
| Hydrochloric Acid SCHEMBL347524 | 0.94 | MAPT (0.42) | MAPTKDM4ESLC22A16SMN1; SMN2GALR3 | |
| Hydrochloric Acid SCHEMBL3032024 | 0.90 | HSD17B10 (0.50) | MAPTKDM4ESLC22A16SMN1; SMN2GALR3 | |
| Hydrochloric Acid SCHEMBL2341008 | 0.90 | HSD17B10 (0.50) | MAPTKDM4ESLC22A16SMN1; SMN2GALR3 | |
| Hydrochloric Acid SCHEMBL30298374 | 0.89 | MAPT (0.44) | MAPTKDM4ESLC22A16SMN1; SMN2GALR3 | |
| Hydrochloric Acid SCHEMBL5479514 | 0.87 | MAPT (0.43) | MAPTKDM4ESLC22A16SMN1; SMN2GALR3 | |
| SCHEMBL3833772 | 0.87 | HSD17B10 (0.52) | MAPTKDM4ESLC22A16SMN1; SMN2GALR3 | |
| SCHEMBL13481161 | 0.87 | USP2 (0.47) | MAPTKDM4ESLC22A16SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL29706626 | 0.87 | MAPT (0.43) | MAPTKDM4ESLC22A16SMN1; SMN2GALR3 | |
| SCHEMBL30603364 | 0.86 | HSD17B10 (0.44) | MAPTKDM4ESLC22A16SMN1; SMN2GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 696 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230083861-A1 | FLOW-AID COMPOSITIONS | CORN PRODUCTS DEVELOPMENT, INC. | 2023-03-16 | — | — | US | claimed |
| EP-4103533-A1 | FLOW-AID COMPOSITIONS | CORN Products Development Inc. (US) | 2022-12-21 | — | — | EP | claimed |
| US-20220361490-A1 | SEED COATING COMPOSITIONS | CORN PRODUCTS DEVELOPMENT, INC. | 2022-11-17 | — | — | US | claimed |
| EP-4033899-A1 | SEED COATING COMPOSITIONS | Corn Products Development, Inc. (US) | 2022-08-03 | — | — | EP | claimed |
| WO-2021162826-A1 | FLOW-AID COMPOSITIONS | CORN PRODUCTS DEVELOPMENT, INC. (US) | 2021-08-19 | — | — | WO | claimed |
| WO-2021061439-A1 | SEED COATING COMPOSITIONS | CORN PRODUCTS DEVELOPMENT, INC. (US) | 2021-04-01 | — | — | WO | claimed |
| CN-109111857-B | Polishing solution and application thereof to polishing of 2.5D zirconia ceramic plate | 北京保利世达科技有限公司 | 2020-10-16 | — | — | CN | claimed |
| EP-2367921-B1 | CLEANING OF A COOKING DEVICE OR APPLIANCE WITH A COMPOSITION COMPRISING A BUILT-IN RINSE AID | DIVERSEY INC (US) | 2020-02-05 | — | — | EP | claimed |
| US-20120118321-A1 | CLEANING OF A COOKING DEVICE OR APPLIANCE WITH A COMPOSITION COMPRISING A BUILT-IN RINSE AID | DIVERSEY, INC. (US) | 2012-05-17 | — | — | US | claimed |
| US-20120058067-A1 | COMPOSITIONS FOR TREATING KERATIN-CONTAINING FIBERS AND MAINTAINING DYED FIBER COLOR INTEGRITY | Kelly Van Gogh, LLC | 2012-03-08 | — | — | US | claimed |
| US-4731162-A | Polysaccharide derivatives containing aldehyde groups for use as paper additives | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1988-03-15 | — | — | US | claimed |
| US-4540778-A | Sulfosuccinate, alkyl- and alkenyl sulfosuccinate, sulfomaleate, and disulfosuccinate half-esters of polygalactomannans | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1985-09-10 | — | — | US | claimed |
| US-4387221-A | Alkyl- and alkenyl-sulfosuccinate starchhalf-esters, a method for the preparation thereof | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1983-06-07 | — | — | US | claimed |
| EP-0025830-B1 | NOVEL STARCH ETHER DERIVATIVES, A METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN PAPER | National Starch and Chemical Corporation (US) | 1983-05-25 | — | — | EP | claimed |
| US-4379919-A | Starch sulfomaleate half-esters, a method for their preparation and their use to prepare starch disulfosuccinate half-esters | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1983-04-12 | — | — | US | claimed |
| US-4276414-A | AMINOMETHYLENEPHOSPHONIC ACIDS | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1981-06-30 | — | — | US | claimed |
| US-4260738-A | FOR USE IN PAPERMAKING | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1981-04-07 | — | — | US | claimed |
| EP-0025830-A1 | Novel starch ether derivatives, a method for the preparation thereof and their use in paper | National Starch and Chemical Corporation (US) | 1981-04-01 | — | — | EP | claimed |
| US-4119487-A | FROM 3-CHLORO-2-SULFOPROPIONIC ACID | NATIONAL STARCH & CHEMICAL CORPORATION (US) | 1978-10-10 | — | — | US | claimed |
| US-3969341-A | Method for the preparation of starch products and the compounds utilized therefor and the product thereof | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1976-07-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058067-A1 | COMPOSITIONS FOR TREATING KERATIN-CONTAINING FIBERS AND MAINTAINING DYED FIBER COLOR INTEGRITY | KRT18, COL1A1, COL14A1 | CHRM2 4599/4885CHRM1 4584/4885CHRM3 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.