Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 6/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 6/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 6/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 6/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 6/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30323388 | 0.77 | ABCG2 (0.42) | KCNH2CACNA1GPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL30323365 | 0.76 | OPRM1 (0.42) | KCNH2CACNA1GALDH1A1OPRL1 | |
| SCHEMBL30323348 | 0.75 | PRKAB2 (0.45) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL30323332 | 0.74 | KMT2A (0.43) | KCNH2ALDH1A1OPRL1 | |
| SCHEMBL22571348 | 0.73 | RXFP1 (0.48) | RXFP1ABCG2 | |
| SCHEMBL22571395 | 0.72 | RXFP1 (0.51) | RXFP1ABCG2 | |
| SCHEMBL30463793 | 0.72 | RXFP1 (0.51) | RXFP1ABCG2 | |
| SCHEMBL22571459 | 0.71 | RXFP1 (0.45) | RXFP1ABCG2 | |
| SCHEMBL30323373 | 0.71 | PRKAB2 (0.39) | KCNH2CACNA1GPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL22571357 | 0.70 | RXFP1 (0.49) | RXFP1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023049199-A1 | AZOLE COMPOUNDS | ZENO MANAGEMENT, INC. (US) | 2023-03-30 | — | — | WO | disclosed |