Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 5/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 5/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 5/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30323406 | 0.88 | PRKAB2 (0.43) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL29888333 | 0.78 | RXFP1 (0.48) | SMORXFP1ABCG2 | |
| SCHEMBL30323432 | 0.75 | KCNH2 (0.39) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL30323410 | 0.73 | ABCG2 (0.44) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL30323350 | 0.71 | MMP1 (0.50) | MMP13ALDH1A1SMN1; SMN2 | |
| SCHEMBL30323372 | 0.71 | SMN1; SMN2 (0.42) | METMMP13ALDH1A1SMN1; SMN2 | |
| SCHEMBL22556334 | 0.69 | RXFP1 (0.53) | RXFP1ABCG2TDP1ALDH1A1RAB9A | |
| SCHEMBL23701602 | 0.69 | RXFP1 (0.53) | SMORXFP1TDP1 | |
| SCHEMBL22556320 | 0.69 | RXFP1 (0.53) | SMORXFP1TDP1 | |
| SCHEMBL23701612 | 0.69 | RXFP1 (0.50) | SMORXFP1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023049199-A1 | AZOLE COMPOUNDS | ZENO MANAGEMENT, INC. (US) | 2023-03-30 | — | — | WO | disclosed |