Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583025 | 0.87 | FFAR1 (0.43) | OPRM1OPRL1SIGMAR1CARM1PRMT6 | |
| SCHEMBL16398438 | 0.85 | CTSL (0.45) | CTSLCTSBCTSKCA1CA2 | |
| SCHEMBL16398437 | 0.85 | CTSL (0.45) | CTSLCTSBCTSKCA1CA2 | |
| SCHEMBL5518662 | 0.83 | BCHE (0.42) | OPRM1OPRL1SIGMAR1CARM1PRMT6 | |
| SCHEMBL5518667 | 0.83 | BCHE (0.42) | OPRM1OPRL1SIGMAR1CARM1PRMT6 | |
| SCHEMBL717952 | 0.82 | OPRM1 (0.49) | OPRM1OPRL1SIGMAR1CARM1PRMT6 | |
| SCHEMBL5523451 | 0.80 | PKM (0.37) | CARM1PRMT6HCRTR2 | |
| SCHEMBL5523447 | 0.80 | PKM (0.37) | CARM1PRMT6HCRTR2 | |
| SCHEMBL25360969 | 0.78 | OPRM1 (0.46) | OPRM1OPRL1SIGMAR1CARM1PRMT6 | |
| SCHEMBL6469380 | 0.78 | OPRM1 (0.59) | OPRM1OPRL1SIGMAR1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240390298-A1 | CYCLOHEXYL BETA-HYDROXY ALKYL AMINES AND MEDICAL USES THEREOF | ATROGI AB (SE) | 2024-11-28 | — | — | US | disclosed |
| EP-4405041-A1 | CYCLOHEXYL BETA-HYDROXY ALKYL AMINES AND MEDICAL USES THEREOF | Atrogi AB (SE) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023046882-A1 | CYCLOHEXYL BETA-HYDROXY ALKYL AMINES AND MEDICAL USES THEREOF | ATROGI AB (SE) | 2023-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240390298-A1 | CYCLOHEXYL BETA-HYDROXY ALKYL AMINES AND MEDICAL USES THEREOF | H1-5, CYP3A5, HRH3 | OPRM1 53/4885OPRL1 264/4885SIGMAR1 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.