Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377134 | 0.91 | KMT2A (0.42) | PPARGPPARDPPARAKMT2AMEN1 | |
| SCHEMBL2214352 | 0.87 | KDM4E (0.42) | PPARGKMT2AMEN1PSEN1PSEN2 | |
| SCHEMBL2214984 | 0.82 | KMT2A (0.38) | KMT2AMEN1PSEN1PSEN2APH1B | |
| SCHEMBL304042 | 0.80 | MAPT (0.46) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL3378121 | 0.80 | MAPT (0.46) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL303353 | 0.77 | LMNA (0.43) | KMT2AMEN1PSEN1PSEN2APH1B | |
| SCHEMBL3377457 | 0.75 | MAPT (0.40) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL3376447 | 0.74 | AVPR2 (0.37) | KMT2AMEN1LMNAGAAHTT | |
| SCHEMBL3376229 | 0.74 | ALDH1A1 (0.53) | LMNAGAAHTTALDH1A1PKM | |
| SCHEMBL3376941 | 0.73 | POLB (0.49) | KMT2AMEN1GAAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500836-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2342177-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-07-13 | — | — | EP | claimed |
| WO-2010023448-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | claimed |