Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31543433 | 0.84 | — | — | |
| SCHEMBL5174730 | 0.78 | COMT (0.46) | COMTMAPTPOLBP2RY1 | |
| Ammonia Solution, Strong SCHEMBL29243356 | 0.76 | COMT (0.44) | COMTMAPTPOLBP2RY1 | |
| SCHEMBL965933 | 0.74 | NOS1 (0.50) | COMTMAPT | |
| SCHEMBL10699580 | 0.74 | ALDH1A1 (0.34) | COMTMAPT | |
| SCHEMBL20465038 | 0.74 | MAPT (0.33) | COMTMAPTPOLB | |
| SCHEMBL20711405 | 0.73 | P2RY1 (0.34) | COMTP2RY1 | |
| SCHEMBL3067173 | 0.71 | ENPP3 (0.33) | — | |
| SCHEMBL12298853 | 0.71 | COMT (0.31) | COMT | |
| SCHEMBL12086423 | 0.71 | POLB (0.34) | COMTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |