Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30329030 | 0.94 | EIF2AK4 (0.47) | EIF2AK4GPR119CYP11B2CYP3A4HIF1A | |
| SCHEMBL30328874 | 0.92 | EIF2AK4 (0.51) | EIF2AK4GPR119CYP11B2CYP3A4HIF1A | |
| SCHEMBL485007 | 0.87 | CYP11B2 (0.59) | GPR119CYP11B2CYP3A4HIF1ACYP2C19 | |
| SCHEMBL2423408 | 0.83 | GPR119 (0.55) | GPR119ALDH1A1 | |
| SCHEMBL13156801 | 0.80 | CYP11B2 (0.52) | EIF2AK4CYP11B2CYP3A4HIF1ACYP2C19 | |
| SCHEMBL30328864 | 0.80 | EIF2AK4 (0.51) | EIF2AK4GPR119CYP11B2CYP3A4HIF1A | |
| SCHEMBL25223238 | 0.77 | CYP11B2 (0.55) | EIF2AK4GPR119CYP11B2CYP3A4HIF1A | |
| SCHEMBL29418501 | 0.77 | CYP11B2 (0.55) | EIF2AK4GPR119CYP11B2CYP3A4HIF1A | |
| SCHEMBL30599714 | 0.77 | CYP11B2 (0.55) | EIF2AK4GPR119CYP11B2CYP3A4HIF1A | |
| SCHEMBL30328838 | 0.77 | EIF2AK4 (0.54) | EIF2AK4GPR119CYP11B2CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |