Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30329217 | 0.86 | ROCK2 (0.40) | PIM1PIM3PIM2ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL30329347 | 0.85 | ROCK2 (0.39) | PIM1PIM3PIM2ALDH1A1HSD17B10 | |
| SCHEMBL30328553 | 0.82 | PIM1 (0.36) | PIM1PIM3PIM2ALDH1A1HSD17B10 | |
| SCHEMBL30327865 | 0.82 | CNR2 (0.37) | PIM1PIM3PIM2ALDH1A1HSD17B10 | |
| SCHEMBL30329246 | 0.80 | PIM1 (0.36) | PIM1PIM3PIM2ALDH1A1HSD17B10 | |
| SCHEMBL25163969 | 0.79 | TSHR (0.41) | PIM1PIM3PIM2ALDH1A1HSD17B10 | |
| SCHEMBL30328597 | 0.76 | PIM1 (0.31) | PIM1PIM3PIM2ALDH1A1HSD17B10 | |
| SCHEMBL30327738 | 0.73 | PIM1 (0.40) | PIM1PIM3PIM2ALDH1A1HSD17B10 | |
| SCHEMBL30328713 | 0.72 | ROCK1 (0.38) | PIM1PIM3PIM2ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL30327910 | 0.72 | PIM1 (0.40) | PIM1PIM3PIM2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |