Acetic Acid

Acetic Acid

SCHEMBL30329967

CC(=O)O.CCCCCCCCCCCC=C1CCCN1C

nearest known ligand 0.39

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.37
ALOX5 P09917 2/20 0.37
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
EP300 Q09472 1/20 0.37
GMNN O75496 1/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36
APEX1 P27695 1/20 0.36
CYP2C19 P33261 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HSD17B10 Q99714 1/20 0.36
DUSP3 P51452 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5936921 0.91 ALOX5 (0.39) ALOX5MAPT
SCHEMBL30330110 0.87 ALOX5 (0.36) ALOX5
Cyanide SCHEMBL30329774 0.86 ALOX5 (0.36) ALOX5MAPT
Acetic Acid SCHEMBL30330046 0.86 INMT (0.38) ALOX5FNTAFNTBEP300LMNA
SCHEMBL30329982 0.83 CCR5 (0.36)
Trifluoromethanesulfonic Acid SCHEMBL30330263 0.82 CCR5 (0.39) ALOX5
Trifluoromethanesulfonic Acid SCHEMBL30330427 0.82 CCR5 (0.39) ALOX5
Acetic Acid SCHEMBL30330055 0.82 CCR5 (0.35) FNTAFNTBEP300
Trifluoromethanesulfonic Acid SCHEMBL30330718 0.81 CCR5 (0.38) ALOX5MAPT
Acetic Acid SCHEMBL30329963 0.80 INMT (0.35) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023046704-A1 ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR Dräger Safety AG & Co. KGaA (DE) 2023-03-30 WO disclosed