Biphenyl

Biphenyl

SCHEMBL303312

C=COC(C)N.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TAAR1 Q96RJ0 4/20 0.37
SLC6A2 P23975 3/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
CYP1A2 P05177 1/20 0.35
GAA P10253 1/20 0.35
CYP2C9 P11712 1/20 0.35
PKM P14618 1/20 0.35
CYP2C19 P33261 1/20 0.35
PDCD1 Q15116 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
CYP3A4 P08684 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAOA P21397 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
CYP2A6 P11509 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL273891 0.79
SCHEMBL11493641 0.79
Water SCHEMBL6141054 0.77
Biphenyl SCHEMBL1556544 0.74 ALDH1A1 (0.60) ALDH1A1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL28909330 0.73 CYP1A2 (0.50) CYP1A2GAACYP2C9PKMCYP2C19
Biphenyl SCHEMBL27426704 0.71 ALDH1A1 (0.56) ALDH1A1TAAR1SLC6A2SLC6A4SLC6A3
Butane SCHEMBL724851 0.70
SCHEMBL23239439 0.70 MAPT (0.44) CYP1A2GAACYP2C9PKMCYP2C19
SCHEMBL8105843 0.70 HCAR2 (0.43) ALDH1A1TAAR1CYP2C19ADRA2AADRA2C
SCHEMBL291361 0.70 HCAR2 (0.43) ALDH1A1TAAR1CYP2C19ADRA2AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10031394-B2 Electrophoretic particle, electrophoretic particle dispersion liquid, display medium, and display device E INK CORPORATION (US) 2018-07-24 US disclosed
US-9152005-B2 Particle dispersion for display, display medium, and display device FUJI XEROX CO., LTD. (JP) 2015-10-06 US disclosed
US-8717282-B2 White particles for display, particle dispersion for display, display medium and display device FUJI XEROX CO., LTD. (JP) 2014-05-06 US disclosed
US-20130222884-A1 ELECTROPHORETIC PARTICLE, PARTICLE DISPERSION LIQUID FOR DISPLAY, DISPLAY MEDIUM AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-20130222888-A1 ELECTROPHORETIC PARTICLE, ELECTROPHORETIC PARTICLE DISPERSION LIQUID, DISPLAY MEDIUM, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-20130222887-A1 ELECTROPHORETIC PARTICLE, ELECTROPHORETIC PARTICLE DISPERSION LIQUID, DISPLAY MEDIUM, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-20130182312-A1 WHITE PARTICLES FOR DISPLAY, PARTICLE DISPERSION FOR DISPLAY, DISPLAY MEDIUM AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2013-07-18 US disclosed
US-8477405-B2 Particle dispersion for display, display medium and display device FUJI XEROX CO., LTD. (JP) 2013-07-02 US disclosed
US-8404881-B2 White particles for display, particle dispersion for display, display medium and display device FUJI XEROX CO., LTD. (JP) 2013-03-26 US disclosed
US-8094365-B2 White particles for display, particle dispersion for display, display medium and display device FUJI XEROX CO., LTD. (JP) 2012-01-10 US disclosed
US-7952793-B2 Electrophoretic particles, electrophoretic particle dispersion, display medium and display device FUJI XEROX CO., LTD. (JP) 2011-05-31 US disclosed
US-20110063714-A1 ELECTROPHORETIC PARTICLES, ELECTROPHORETIC PARTICLE DISPERSION, DISPLAY MEDIUM AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2011-03-17 US disclosed
US-7855829-B2 Particles for display, particle dispersion for display, display medium and display device FUJI XEROX CO., LTD. (JP) 2010-12-21 US disclosed
US-7796323-B2 Display particle and method for producing the same, display particle dispersion, display medium, and display device FUJI XEROX CO., LTD. (JP) 2010-09-14 US disclosed
US-20100225998-A1 PARTICLES FOR DISPLAY, PARTICLE DISPERSION FOR DISPLAY, DISPLAY MEDIUM AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2010-09-09 US disclosed
US-20100225228-A1 WHITE PARTICLES FOR DISPLAY, PARTICLE DISPERSION FOR DISPLAY, DISPLAY MEDIUM AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2010-09-09 US disclosed
US-20100225997-A1 WHITE PARTICLES FOR DISPLAY, PARTICLE DISPERSION FOR DISPLAY, DISPLAY MEDIUM AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2010-09-09 US disclosed
US-20100225575-A1 PARTICLE DISPERSION FOR DISPLAY, DISPLAY MEDIUM AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2010-09-09 US disclosed
US-20090201569-A1 DISPLAY PARTICLE AND METHOD FOR PRODUCING THE SAME, DISPLAY PARTICLE DISPERSION, DISPLAY MEDIUM, AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2009-08-13 US disclosed
US-5689779-A Liquid developer and developing method and developing apparatus using same MINOLTA CO., LTD. (JP) 1997-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100225228-A1 WHITE PARTICLES FOR DISPLAY, PARTICLE DISPERSION FOR DISPLAY, DISPLAY MEDIUM AND DISPLAY DEVICE SIGLEC7, SELP, FUCA2 ALDH1A1 959/4885TAAR1 1002/4885SLC6A2 2411/4885
US-20100225997-A1 WHITE PARTICLES FOR DISPLAY, PARTICLE DISPERSION FOR DISPLAY, DISPLAY MEDIUM AND DISPLAY DEVICE PLD1, SELP, PLD2 ALDH1A1 2844/4885TAAR1 2692/4885SLC6A2 3246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.