Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 4/20 | 0.44 |
| ▸ | JAK1 | P23458 | 4/20 | 0.44 |
| ▸ | TYK2 | P29597 | 4/20 | 0.44 |
| ▸ | JAK3 | P52333 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30332533 | 0.81 | DPP4 (0.43) | JAK2JAK1TYK2JAK3FEN1 | |
| SCHEMBL30332524 | 0.80 | CCNT1 (0.47) | PIM1JAK2JAK1TYK2JAK3 | |
| SCHEMBL30332252 | 0.79 | DPP4 (0.41) | PIM1JAK2JAK1TYK2JAK3 | |
| SCHEMBL30023798 | 0.72 | FFAR1 (0.47) | PIM1JAK2JAK1TYK2JAK3 | |
| SCHEMBL30607659 | 0.71 | DPP4 (0.41) | ALOX5APDPP4 | |
| SCHEMBL15782893 | 0.68 | FFAR1 (0.51) | PIM1FFAR1ALOX5APFEN1LRRK2 | |
| SCHEMBL20400196 | 0.68 | FFAR1 (0.48) | PIM1FFAR1ALOX5APFEN1PDK2 | |
| SCHEMBL30291170 | 0.68 | FFAR1 (0.45) | PIM1JAK2JAK1TYK2JAK3 | |
| Hydrochloric Acid SCHEMBL23853012 | 0.68 | FFAR1 (0.48) | PIM1JAK2JAK1TYK2JAK3 | |
| SCHEMBL22182433 | 0.68 | FFAR1 (0.45) | PIM1JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023046128-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-30 | — | — | WO | disclosed |