Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 10/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.41 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30331919 | 0.81 | PIM1 (0.45) | DPP4METPDK2JAK2JAK1 | |
| SCHEMBL30332368 | 0.80 | DPP4 (0.51) | DPP4PRMT5WDR77METKIT | |
| SCHEMBL30332259 | 0.78 | JAK2 (0.45) | METKITPDK2JAK2JAK1 | |
| SCHEMBL30332252 | 0.74 | DPP4 (0.41) | DPP4PDK2JAK2JAK1TYK2 | |
| SCHEMBL22918695 | 0.71 | PRMT5 (0.53) | PRMT5WDR77METKITPDK2 | |
| SCHEMBL439097 | 0.70 | DPP4 (0.63) | DPP4 | |
| SCHEMBL11826508 | 0.70 | L3MBTL1 (0.61) | PRMT5WDR77METKITPDK2 | |
| SCHEMBL5616194 | 0.69 | DPP4 (0.59) | DPP4 | |
| SCHEMBL30332536 | 0.68 | CYP2A6 (0.56) | DPP4CYP2C9 | |
| SCHEMBL9400328 | 0.68 | CYP2A6 (0.56) | DPP4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023046128-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-30 | — | — | WO | disclosed |