SCHEMBL303331

SCHEMBL303331

O=C1C=C(c2ccccc2)C(=O)N1c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.51
NPSR1 Q6W5P4 5/20 0.51
GAA P10253 4/20 0.51
MAPT P10636 4/20 0.51
CCR6 P51684 2/20 0.51
HPGD P15428 2/20 0.51
ALOX12 P18054 2/20 0.51
CACNA1B Q00975 2/20 0.51
APBA1 Q02410 2/20 0.51
MGLL Q99685 3/20 0.48
FAAH O00519 2/20 0.47
HTT P42858 2/20 0.45
LMNA P02545 2/20 0.45
HSP90AA1 P07900 2/20 0.43
PKM P14618 1/20 0.43
ATM Q13315 1/20 0.43
BACE1 P56817 1/20 0.42
RGS4 P49798 1/20 0.41
HCRTR1 O43613 1/20 0.41
S1PR4 O95977 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1471161 0.89 MAPT (0.50) ALDH1A1NPSR1GAAMAPTCCR6
SCHEMBL28170453 0.88 NPSR1 (0.47) ALDH1A1NPSR1GAAMAPTCCR6
SCHEMBL1471657 0.88 MAPT (0.54) ALDH1A1NPSR1GAAMAPTCCR6
SCHEMBL1473687 0.88 MGLL (0.47) ALDH1A1NPSR1GAAMAPTCCR6
SCHEMBL1471136 0.88 MGLL (0.47) ALDH1A1NPSR1GAAMAPTCCR6
SCHEMBL1471189 0.88 ALDH1A1 (0.57) ALDH1A1NPSR1GAAMAPTCCR6
SCHEMBL1471536 0.88 RGS4 (0.57) ALDH1A1NPSR1GAAMAPTCCR6
SCHEMBL1473349 0.88 MAPT (0.57) ALDH1A1NPSR1GAAMAPTCCR6
SCHEMBL28976650 0.88 ALDH1A1 (0.45) ALDH1A1NPSR1GAAMAPTCCR6
SCHEMBL4385777 0.86 MGLL (0.49) ALDH1A1NPSR1GAAMAPTCCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190015302-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2019-01-17 US claimed
EP-3397718-A1 FLUORESCENT PARTICULATE MATERIAL L'Oréal (FR) 2018-11-07 EP claimed
CN-105418937-B Single white light star polymer of a kind of 12 arms and preparation method thereof 福建师范大学 2018-04-13 CN claimed
WO-2017114877-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2017-07-06 WO claimed
CN-105418937-A Twelve-arm single-white-light star polymer and preparation method thereof UNIV FUJIAN 2016-03-23 CN claimed
EP-2536737-A1 A METHOD FOR PREPARATION OF THE TETRASACCHARIDE LACTO-N-NEOTETRAOSE (LNNT) CONTAINING N-ACETYLLACTOSAMINE Glycom A/S (DK) 2012-12-26 EP claimed
JP-2012500860-A 2012-01-12 JP claimed
WO-2011100980-A1 A METHOD FOR PREPARATION OF THE TETRASACCHARIDE LACTO-N-NEOTETRAOSE (LNNT) CONTAINING N-ACETYLLACTOSAMINE GLYCOM A/S (DK) 2011-08-25 WO claimed
WO-2011054731-A1 FLUORESCENT MATERIALS BASF SE (DE) 2011-05-12 WO claimed
EP-2091531-B1 PHENYL SUBSTITUTED MALEIMIDES AS MEDICAMENTS FOR BLOCKING DEGENERATIVE TISSUE DAMAGES BY INHIBITING MPT CONGENIA S R L (IT) 2010-11-24 EP claimed
EP-1937779-A1 ENCAPSULATED LUMINESCENT PIGMENTS Ciba Holding Inc. (CH) 2008-07-02 EP claimed
WO-2008067863-A2 PHENYL SUBSTITUTED MALEIMIDES AS MEDICAMENTS FOR BLOCKING DEGENERATIVE TISSUE DAMAGES BY INHIBITING MPT CONGENIA S.R.L. (IT) 2008-06-12 WO claimed
WO-2008017593-A1 NOVEL POLYHEDRAL OLIGOMERIC SILSESQUIOXANE (POSS) BASED FLUORESCENT COLORANTS CIBA HOLDING INC. (CH) 2008-02-14 WO claimed
US-20080029739-A1 Novel polyhedral oligomeric silsesquioxane (POSS) based fluorescent colorants CIBA SPECIALTY CHEMICALS CORP. 2008-02-07 US claimed
EP-1883676-A1 FUNCTIONALIZED NANOPARTICLES Ciba Specialty Chemicals Holding Inc. (CH) 2008-02-06 EP claimed
US-20070221884-A1 Liminescent Silicon Oxide Flakes CIBA SPECIALTY CHEMICALS CORP. 2007-09-27 US claimed
WO-2007042438-A1 ENCAPSULATED LUMINESCENT PIGMENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-04-19 WO claimed
EP-1769049-A2 LUMINESCENT SILICON OXIDE FLAKES Ciba Specialty Chemicals Holding Inc. (CH) 2007-04-04 EP claimed
WO-2006125736-A1 FUNCTIONALIZED NANOPARTICLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-11-30 WO claimed
WO-2006008239-A2 LUMINESCENT SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190015302-A1 FLUORESCENT PARTICULATE MATERIAL HNRNPM, NPM1, HNRNPF ALDH1A1 677/4885NPSR1 776/4885GAA 2434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.