Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26215299 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LTA4HPTGS2MAPTKDM4E | |
| Dinitrophenylene SCHEMBL27323145 | 0.94 | LMNA (0.55) | ALDH1A1LTA4HPTGS2MAPTKDM4E | |
| SCHEMBL24168437 | 0.89 | MAPT (0.54) | ALDH1A1LTA4HPTGS2MAPTKDM4E | |
| SCHEMBL9157220 | 0.88 | ALDH1A1 (0.51) | ALDH1A1LTA4HPTGS2MAPTKDM4E | |
| SCHEMBL8152290 | 0.88 | MAPT (0.48) | ALDH1A1LTA4HPTGS2MAPTKDM4E | |
| SCHEMBL9158141 | 0.87 | ALDH1A1 (0.67) | ALDH1A1LTA4HPTGS2MAPTKDM4E | |
| SCHEMBL9356592 | 0.87 | ALDH1A1 (0.67) | ALDH1A1LTA4HPTGS2MAPTKDM4E | |
| SCHEMBL2576415 | 0.85 | ALDH1A1 (0.61) | ALDH1A1LTA4HMAPTKDM4ENPSR1 | |
| SCHEMBL8999322 | 0.85 | ALDH1A1 (0.54) | ALDH1A1LTA4HPTGS2MAPTKDM4E | |
| SCHEMBL1242359 | 0.85 | MEN1 (0.59) | ALDH1A1LTA4HPTGS2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490201-A | Inhibitors of YAP/TAZ-TEAD tumor proteins, their synthesis and use | 布里奇恩生物科学公司 | 2023-07-25 | — | — | CN | disclosed |
| EP-4175658-A1 | INHIBITORS OF YAP/TAZ-TEAD ONCOPROTEINS, SYNTHESIS AND USE THEREOF | Bridgene Biosciences, Inc. (US) | 2023-05-10 | — | — | EP | disclosed |