SCHEMBL3033576

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13217615	0.77	NPC1 (0.62)	KMT2AL3MBTL1LMNANPC1ALDH1A1
	SCHEMBL7148530	0.74	CYP3A4 (0.72)	KMT2AL3MBTL1LMNANPC1CYP3A4
	SCHEMBL11694008	0.73	TDP1 (0.65)	L3MBTL1LMNANPC1CYP3A4ALDH1A1
	SCHEMBL13217620	0.73	NPC1 (0.49)	KMT2AL3MBTL1LMNANPC1SMN1; SMN2
	SCHEMBL4904756	0.72	ALDH1A1 (0.50)	L3MBTL1LMNANPC1CYP3A4ALDH1A1
	SCHEMBL109197	0.72	ALDH1A1 (0.64)	KMT2AL3MBTL1LMNANPC1CYP3A4
	SCHEMBL7495851	0.72	CYP3A4 (0.64)	KMT2AL3MBTL1LMNANPC1CYP3A4
	SCHEMBL30992968	0.72	CYP3A4 (0.68)	L3MBTL1LMNANPC1CYP3A4ALDH1A1
	SCHEMBL547618	0.72	CYP3A4 (0.68)	L3MBTL1LMNANPC1CYP3A4ALDH1A1
	SCHEMBL25201619	0.71	HPGD (0.67)	KMT2AL3MBTL1LMNANPC1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.