Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2514952 | 1.00 | KMT2A (0.51) | KMT2ALMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL2514931 | 0.98 | KMT2A (0.50) | KMT2ALMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL27479651 | 0.91 | TSHR (0.48) | KMT2ALMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL20298354 | 0.88 | ALDH1A1 (0.57) | KMT2ALMNATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL28996119 | 0.88 | HSD17B10 (0.56) | KMT2ALMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL15572574 | 0.85 | KMO (0.47) | KMT2ALMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL15572594 | 0.85 | KMO (0.47) | KMT2ALMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL15572964 | 0.85 | KMO (0.47) | KMT2ALMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL15573500 | 0.85 | KMO (0.47) | KMT2ALMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL2829058 | 0.80 | LMNA (0.53) | KMT2ALMNATSHRSMN1; SMN2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2023083330-A1 | DRAK2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 百极优棠(广东)医药科技有限公司 | 2023-05-19 | — | — | WO | disclosed |