Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CLPP | Q16740 | 2/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980919 | 1.00 | KMT2A (0.46) | KMT2AMEN1DRD4TRPV6ALDH1A1 | |
| SCHEMBL30336976 | 0.89 | KMT2A (0.55) | KMT2AMEN1DRD4CLPPACHE | |
| SCHEMBL30337066 | 0.88 | FAAH (0.48) | — | |
| SCHEMBL30337505 | 0.87 | ALDH1A1 (0.46) | KMT2AMEN1TRPV6ALDH1A1CLPP | |
| SCHEMBL30337060 | 0.84 | KMT2A (0.49) | KMT2AMEN1DRD4CLPPACHE | |
| SCHEMBL30337139 | 0.84 | MCHR1 (0.42) | KMT2ADRD4ACHEPKM | |
| SCHEMBL26092261 | 0.82 | KMT2A (0.41) | KMT2ADRD4ACHEPKM | |
| SCHEMBL30337305 | 0.82 | HTR1A (0.43) | KMT2AALDH1A1KDM4EACHEPKM | |
| SCHEMBL28980922 | 0.82 | HTR1A (0.40) | DRD4ALDH1A1CLPPKDM4ETDP1 | |
| SCHEMBL30337511 | 0.80 | KMT2A (0.43) | KMT2ACLPPACHEPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916206-A | Novel compound and pharmaceutical composition for preventing or treating resistant cancer comprising same | 治愈医药社株式会社 | 2023-04-04 | — | — | CN | disclosed |