Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337300 | 0.94 | HTR1A (0.45) | HTR1AKDM4EALDH1A1POLBHPGD | |
| SCHEMBL30337305 | 0.89 | HTR1A (0.43) | HTR1AKDM4EALDH1A1POLBHPGD | |
| SCHEMBL24145803 | 0.88 | ENPP2 (0.48) | HTR1AALDH1A1ENPP2GRM2THRB | |
| SCHEMBL30337246 | 0.86 | ENPP2 (0.47) | HTR1ASMN1; SMN2ENPP2GRM2THRB | |
| SCHEMBL30337060 | 0.86 | KMT2A (0.49) | HTR1AENPP2 | |
| SCHEMBL30337191 | 0.84 | HTR1A (0.47) | HTR1AENPP2THRB | |
| SCHEMBL30337119 | 0.84 | HTR1A (0.48) | HTR1AKDM4EALDH1A1POLBHPGD | |
| SCHEMBL30337166 | 0.81 | KDM4E (0.43) | HTR1AKDM4EALDH1A1POLBENPP2 | |
| SCHEMBL22164678 | 0.81 | GRM2 (0.37) | HTR1AKDM4EALDH1A1POLBHPGD | |
| SCHEMBL24153613 | 0.81 | NPY1R (0.36) | HTR1ASMN1; SMN2ENPP2GRM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916206-A | Novel compound and pharmaceutical composition for preventing or treating resistant cancer comprising same | 治愈医药社株式会社 | 2023-04-04 | — | — | CN | disclosed |