Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337569 | 0.94 | KDM4E (0.46) | KDM4EPOLBHTTFAAHALDH1A1 | |
| SCHEMBL30337191 | 0.85 | HTR1A (0.47) | HTR1AENPP2THRBDRD2 | |
| SCHEMBL24145803 | 0.84 | ENPP2 (0.48) | FAAHALDH1A1HTR1AENPP2THRB | |
| SCHEMBL30337246 | 0.83 | ENPP2 (0.47) | HTR1AENPP2THRBDRD2GRM2 | |
| SCHEMBL30337060 | 0.83 | KMT2A (0.49) | FAAHHTR1AENPP2 | |
| SCHEMBL30337235 | 0.81 | HTR1A (0.43) | KDM4EPOLBALDH1A1HTR1AENPP2 | |
| SCHEMBL30337245 | 0.79 | HTR1A (0.47) | KDM4EPOLBHTTFAAHALDH1A1 | |
| SCHEMBL30337145 | 0.79 | KDM4E (0.45) | KDM4EPOLBHTTFAAHALDH1A1 | |
| SCHEMBL24939876 | 0.78 | HDAC1 (0.41) | POLBALDH1A1ENPP2MAPT | |
| SCHEMBL24145684 | 0.78 | FAAH (0.39) | FAAHALDH1A1HTR1AENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916206-A | Novel compound and pharmaceutical composition for preventing or treating resistant cancer comprising same | 治愈医药社株式会社 | 2023-04-04 | — | — | CN | disclosed |