SCHEMBL30338355

SCHEMBL30338355

CC(CC#N)(c1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MEN1 O00255 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
NPY2R P49146 1/20 0.32
KMT2A Q03164 1/20 0.32
MAOB P27338 2/20 0.32
PYCR1 P32322 1/20 0.32
CTSK P43235 2/20 0.31
CTSS P25774 2/20 0.31
MAOA P21397 1/20 0.31
KIF11 P52732 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3045851 0.83 CYP2A6 (0.33) CYP2A6ALDH1A1MAOBPYCR1CTSK
SCHEMBL9398476 0.79 ESR1 (0.50) ALDH1A1MEN1KMT2AESR1ESR2
SCHEMBL30338404 0.79 MAPT (0.39) ALDH1A1MEN1CYP2D6CYP2C9CYP2C19
SCHEMBL5645124 0.78 CYP2D6 (0.49) ALDH1A1MEN1CYP2D6CYP2C9CYP2C19
SCHEMBL30338171 0.71 SHBG (0.40) CYP2A6ALDH1A1MEN1KMT2AESR1
SCHEMBL30338469 0.71 CYP2A6 (0.38) CYP2A6ALDH1A1MEN1KMT2AESR1
SCHEMBL13578 0.71 CYP2A6 (0.38) CYP2A6ALDH1A1MEN1KMT2AMAOB
SCHEMBL1141384 0.71 CA1 (0.34) CYP2A6ALDH1A1KMT2AMAOBPYCR1
SCHEMBL20782023 0.70 APP (0.47) ALDH1A1ESR1ESR2HSD17B10
SCHEMBL8503879 0.69 ESR1 (0.44) CYP2A6ALDH1A1CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111362833-B Double anthracene D-delta-A type deep blue organic fluorescent material and preparation method and application thereof 陕西师范大学 2023-04-25 CN disclosed