Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558332 | 0.94 | KIF11 (0.44) | CYP2A6ALDH1A1MAOAMAOBKIF11 | |
| SCHEMBL14059544 | 0.88 | RORC (0.33) | ALDH1A1RORCRECQLMAPK1MEN1 | |
| SCHEMBL6563317 | 0.87 | KIF11 (0.41) | ALDH1A1KIF11RORCESR1ESR2 | |
| SCHEMBL11044204 | 0.80 | KIF11 (0.52) | ALDH1A1KIF11RORCESR1ESR2 | |
| SCHEMBL307338 | 0.78 | TSHR (0.52) | CYP2A6ALDH1A1KIF11RORCESR1 | |
| SCHEMBL27915264 | 0.77 | CA1 (0.35) | CYP2A6ALDH1A1MAOAMAOBKIF11 | |
| SCHEMBL29452926 | 0.77 | CYP2A6 (0.35) | CYP2A6ALDH1A1MAOAMAOBKIF11 | |
| SCHEMBL23802020 | 0.76 | CYP19A1 (0.41) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL358617 | 0.76 | MAPT (0.43) | ALDH1A1KIF11RORCESR1ESR2 | |
| SCHEMBL11055 | 0.76 | APP (0.36) | KIF11RORCESR1ESR2SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100526291-C | Method for preparing alpha, alpha-dimethyl-4-bromobenzylcyanide | SHANGHAI INST OF CHEMICAL REAG (CN) | 2009-08-12 | — | — | CN | claimed |
| CN-100475780-C | Production of alpha, alpha-dimethyl-4-brombenethane | SHANGHAI CHEMICAL REAGENT RES (CN) | 2009-04-08 | — | — | CN | claimed |
| CN-1778792-A | Production of alpha, alpha-dimethyl-4-brombenethane | SHANGHAI CHEMICAL REAGENTS INS (CN) | 2006-05-31 | — | — | CN | claimed |
| CN-1626508-A | Method for preparing alpha, alpha-dimethyl-4-bromobenzylcyanide | SHANGHAI INST OF CHEMICAL REAG (CN) | 2005-06-15 | — | — | CN | claimed |
| EP-4720037-A1 | CYP26B1 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | 16380026 Canada Inc. (CA) | 2026-04-08 | — | — | EP | disclosed |
| EP-4720036-A1 | CYP26B1 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | 16380026 Canada Inc. (CA) | 2026-04-08 | — | — | EP | disclosed |
| US-12577245-B2 | Sulfonyl benzamide derivatives as Bcl-2 inhibitors | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2026-03-17 | — | — | US | disclosed |
| EP-4635942-A1 | QUINOLINE DERIVATIVE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Carephar Pharmaceutical Co., Ltd (CN) | 2025-10-22 | — | — | EP | disclosed |
| US-12398120-B2 | Substituted hydantoinamides as ADAMTS7 antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2025-08-26 | — | — | US | disclosed |
| CN-119119033-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-12-13 | — | — | CN | disclosed |
| WO-2024243692-A1 | CYP26B1 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2024-12-05 | — | — | WO | disclosed |
| US-20240317686-A1 | RORyT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2024-09-26 | — | — | US | disclosed |
| CN-1333766-A | Substituted (aminoiminomethyl or aminomethyl) benzoheteroaryl compounds as factor xainhibitors | AVENTIS PHARM PROD INC (US) | 2002-01-30 | — | — | CN | disclosed |
| EP-1140901-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL)BENZOHETEROARYL COMPOUNDS AS FACTOR XA INHIBITORS | Aventis Pharmaceuticals Products Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001014358-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL) DIHYDROBENZOFURANS AND BENOZOPYRANS | AVENTIS PHARMACEUTICALS INC. (DE) | 2001-03-01 | — | — | WO | disclosed |
| WO-2000039087-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL)BENZOHETEROARYL COMPOUNDS AS FACTOR XA INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-07-06 | — | — | WO | disclosed |
| WO-1997042168-A1 | THIO DERIVATIVES OF HYDROXAMIC ACIDS | ZENECA LIMITED (GB) | 1997-11-13 | — | — | WO | disclosed |
| EP-0163551-B1 | PHENOTHIAZINE COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-08-12 | — | — | EP | disclosed |
| US-4705854-A | ANTIALLERGENS, ANTIHISTAMINES | BURROUGHS WELLCOME CO. (US) | 1987-11-10 | — | — | US | disclosed |
| EP-0163551-A1 | Phenothiazine compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577245-B2 | Sulfonyl benzamide derivatives as Bcl-2 inhibitors | BCL2A1, BCL2L1, BCL2L11 | CYP2A6 118/4885ALDH1A1 1756/4885MAOA 4104/4885 |
| US-12398120-B2 | Substituted hydantoinamides as ADAMTS7 antagonists | ADAMTS7, MMP7, ADAM17 | CYP2A6 3551/4885ALDH1A1 3828/4885MAOA 1338/4885 |
| US-20240317686-A1 | RORyT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | RORC, RORB, RORA | CYP2A6 485/4885ALDH1A1 1160/4885MAOA 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.