Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 10/20 | 0.59 |
| ▸ | NPC1 | O15118 | 10/20 | 0.58 |
| ▸ | RAB9A | P51151 | 10/20 | 0.58 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | PKM | P14618 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MLNR | O43193 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29057074 | 1.00 | STAT3 (0.59) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL27135769 | 0.86 | STAT3 (0.60) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL30268164 | 0.85 | STAT3 (0.61) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL30268493 | 0.85 | STAT3 (0.61) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29056990 | 0.84 | STAT3 (0.59) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL30339343 | 0.84 | STAT3 (0.59) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL27135189 | 0.83 | STAT3 (0.70) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25063293 | 0.81 | PRSS12 (0.41) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL30142680 | 0.80 | ATG4B (0.49) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL30142903 | 0.80 | LMNA (0.55) | STAT3NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472292-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| EP-4157888-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2023-04-05 | — | — | EP | disclosed |