SCHEMBL303391

SCHEMBL303391

CSC1Sc2ccccc2N1c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ POLB P06746 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ PTGS1 P23219 2/20 0.30
▸ PTGS2 P35354 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4822999 0.77 MAOA (0.41) MAOAALDH1A1RAB9ASMN1; SMN2POLB
SCHEMBL30923520 0.77 MAOA (0.41) MAOAALDH1A1RAB9ASMN1; SMN2POLB
SCHEMBL16470329 0.77 MAOA (0.36) MAOAKDM4ENPC1ALDH1A1HPGD
Iodide SCHEMBL7694591 0.75 MAOA (0.39) MAOAALDH1A1RAB9ASMN1; SMN2POLB
SCHEMBL30436376 0.73 GAA (0.37) MAOAKDM4ENPC1ALDH1A1HPGD
SCHEMBL28044091 0.73 POLB (0.33) MAOAKDM4ENPC1ALDH1A1HPGD
SCHEMBL11388416 0.73 POLB (0.33) MAOAKDM4ENPC1ALDH1A1HPGD
SCHEMBL4983323 0.73 POLB (0.33) MAOAKDM4ENPC1ALDH1A1HPGD
SCHEMBL28899866 0.73 GAA (0.37) MAOAKDM4ENPC1ALDH1A1HPGD
SCHEMBL514686 0.72 ALDH1A1 (0.35) MAOAALDH1A1HPGDSMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11332779-B2 Nucleic acid melting analysis with saturation dyes BIOFIRE DEFENSE, LLC (US) 2022-05-17 — — US disclosed
CN-109554122-B Curing adhesive for polarizing film, optical film, and image display device 日东电工株式会社 2022-03-01 — — CN disclosed
CN-109536046-B Curing adhesive for polarizing film, optical film, and image display device 日东电工株式会社 2021-06-11 — — CN disclosed
CN-106661386-B Method for manufacturing laminated optical film 日东电工株式会社 2020-10-23 — — CN disclosed
US-20200248247-A1 Nucleic Acid Melting Analysis with Saturation Dyes UNIVERSITY OF UTAH 2020-08-06 — — US disclosed
EP-2826867-B1 Nucleic acid melting analysis with saturation dyes UNIV UTAH RES FOUND (US) 2020-06-03 — — EP disclosed
US-10655169-B2 Nucleic acid melting analysis with saturation dyes UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2020-05-19 — — US disclosed
CN-105849598-B Laminated polarizing film, method for producing same, laminated optical film, and image display device 日东电工株式会社 2020-02-07 — — CN disclosed
CN-109554122-A Polarizing coating curing type adhesive, polarizing coating, optical film and image display device 日东电工株式会社 2019-04-02 — — CN disclosed
CN-109536046-A Polarizing coating curing type adhesive, polarizing coating, optical film and image display device 日东电工株式会社 2019-03-29 — — CN disclosed
EP-1558762-A4 AMPLICON MELTING ANALYSIS WITH SATURATION DYES UNIV UTAH RES FOUND (US) 2008-06-25 — — EP disclosed
US-7387887-B2 Nucleic acid melting analysis with saturation dyes UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2008-06-17 — — US disclosed
EP-1774047-A2 NUCLEIC ACID MELTING ANALYSIS WITH SATURATION DYES University of Utah Research Foundation (US) 2007-04-18 — — EP disclosed
US-20070020672-A1 Nucleic acid melting analysis with saturation dyes IDAHO TECHNOLOGY, INC. (US) 2007-01-25 — — US disclosed
WO-2006121423-A2 NUCLEIC ACID MELTING ANALYSIS WITH SATURATION DYES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2006-11-16 — — WO disclosed
US-20060019253-A1 Polymerase chain reaction analysis by mixing a dsDNA binding dye with a sample of target nucleic acid and primers configured for amplifying; melting the amplified target nucleic acid to generate a melting curve; plotting; repeating; comparison; melting curve difference for each target nucleic acid NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-01-26 — — US disclosed
US-20050233335-A1 standard PCR solution with additional saturating double-stranded (ds) DNA binding dye; fluorescence; cyanine dyes UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2005-10-20 — — US disclosed
EP-1558762-A2 AMPLICON MELTING ANALYSIS WITH SATURATION DYES University of Utah Research Foundation (US) 2005-08-03 — — EP disclosed
WO-2004038038-A2 AMPLICON MELTING ANALYSIS WITH SATURATION DYES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2004-05-06 — — WO disclosed
CN-1295677-A Method and apparatus for accelerated orthokeratology EASTA PHARMACEUTICALS INC (US) 2001-05-16 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060019253-A1 Polymerase chain reaction analysis by mixing a dsDNA binding dye with a sample of target nucleic acid and primers configured for amplifying; melting the amplified target nucleic acid to generate a melting curve; plotting; repeating; comparison; melting curve difference for each target nucleic acid POLL, DNA2, POLRMT MAOA 2383/4885KDM4E 4297/4885NPC1 4424/4885
US-20070020672-A1 Nucleic acid melting analysis with saturation dyes DNA2, POLL, POLRMT MAOA 3291/4885KDM4E 4756/4885NPC1 1279/4885
US-20050233335-A1 standard PCR solution with additional saturating double-stranded (ds) DNA binding dye; fluorescence; cyanine dyes DDB1, POLL, POLRMT MAOA 4663/4885KDM4E 4574/4885NPC1 2288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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