Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.66 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.66 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.58 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.58 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.56 |
| ▸ | LDLR | P01130 | 1/20 | 0.56 |
| ▸ | KIT | P10721 | 1/20 | 0.56 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 11/20 | 0.55 |
| ▸ | BCR | P11274 | 10/20 | 0.55 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.54 |
| ▸ | HCK | P08631 | 2/20 | 0.54 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.54 |
| ▸ | BTK | Q06187 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24070473 | 1.00 | MAPK14 (0.66) | MAPK14MAP3K20MAP3K7MAP4K2NR2E1 | |
| SCHEMBL30447296 | 0.90 | MAPK14 (0.69) | MAPK14MAP3K20MAP3K7MAP4K2NR2E1 | |
| SCHEMBL24070682 | 0.90 | MAPK14 (0.69) | MAPK14MAP3K20MAP3K7MAP4K2NR2E1 | |
| SCHEMBL4789491 | 0.89 | ABL1 (0.69) | MAPK14MAP3K20MAP3K7MAP4K2NR2E1 | |
| SCHEMBL3424818 | 0.84 | MAPK14 (0.62) | MAPK14MAP3K20MAP3K7MAP4K2NR2E1 | |
| SCHEMBL4788636 | 0.82 | EPHB2 (0.59) | MAPK14MAP3K20MAP3K7MAP4K2NR2E1 | |
| SCHEMBL29514885 | 0.81 | ABL1 (0.78) | MAPK14MAP3K20MAP3K7MAP4K2NR2E1 | |
| SCHEMBL14953321 | 0.81 | ABL1 (0.78) | MAPK14MAP3K20MAP3K7MAP4K2NR2E1 | |
| SCHEMBL4788638 | 0.81 | CSF1R (0.69) | MAPK14MAP3K20MAP3K7MAP4K2NR2E1 | |
| SCHEMBL24070548 | 0.81 | NR2E1 (0.69) | MAPK14MAP3K20MAP3K7MAP4K2NR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227447-A1 | BENZYLAMINE DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-07-20 | — | — | US | disclosed |
| EP-4157447-A1 | BENZYLAMINE DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2023-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227447-A1 | BENZYLAMINE DERIVATIVES AS DDRS INHIBITORS | DDR2, DDR1, DDRGK1 | MAPK14 2850/4885MAP3K20 459/4885MAP3K7 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.