Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340155 | 0.94 | MDM2 (0.48) | EPHX2MDM2CTSBCTSSCTSK | |
| SCHEMBL2367217 | 0.82 | MDM2 (0.56) | EPHX2MDM2CTSBCTSSCTSK | |
| SCHEMBL30229655 | 0.81 | SLC7A5 (0.47) | EPHX2MDM2KLK5MDM4TP53 | |
| SCHEMBL14598321 | 0.80 | CTSS (0.47) | MDM2CTSBCTSSCTSKPTPN1 | |
| SCHEMBL28741567 | 0.77 | CTSL (0.52) | EPHX2MDM2CTSBCTSSCTSK | |
| SCHEMBL16574853 | 0.77 | EPHX2 (0.46) | EPHX2MDM2MDM4TP53PTPN1 | |
| SCHEMBL30278733 | 0.77 | PTPN1 (0.44) | MDM2KLK5MDM4TP53PTPN1 | |
| SCHEMBL22108932 | 0.77 | PTPN1 (0.44) | MDM2KLK5MDM4TP53PTPN1 | |
| SCHEMBL22454530 | 0.77 | MDM4 (0.47) | MDM2MDM4TP53PTPN1 | |
| SCHEMBL29633732 | 0.77 | MDM4 (0.47) | MDM2MDM4TP53PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024200819-A1 | PROTEASE INHIBITORS FOR CORONAVIRAL INFECTIONS | PROTINHI B.V. (NL) | 2024-10-03 | — | — | WO | disclosed |
| EP-4408454-A1 | PROTEASE INHIBITORS | Protinhi B.V. (NL) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023052636-A1 | PROTEASE INHIBITORS | PROTINHI B.V. (NL) | 2023-04-06 | — | — | WO | disclosed |