Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 8/20 | 0.61 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.61 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.58 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3859672 | 0.86 | PDCD1 (0.50) | PDCD1CD274ITGA4ITGB7ALDH1A1 | |
| SCHEMBL6375427 | 0.86 | ITGA4 (0.73) | ITGA4ITGB7ATML3MBTL1ALDH1A1 | |
| SCHEMBL6375429 | 0.86 | ITGA4 (0.73) | ITGA4ITGB7ATML3MBTL1ALDH1A1 | |
| SCHEMBL3859676 | 0.86 | PDCD1 (0.50) | PDCD1CD274ITGA4ITGB7ALDH1A1 | |
| SCHEMBL10013398 | 0.86 | ALDH1A1 (0.53) | PDCD1CD274ITGA4ITGB7ATM | |
| SCHEMBL30102611 | 0.84 | PDCD1 (0.58) | PDCD1CD274 | |
| SCHEMBL2247336 | 0.82 | ITGA4 (0.53) | ITGA4ITGB7ATML3MBTL1ALDH1A1 | |
| SCHEMBL20999193 | 0.82 | CD274 (0.67) | PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL29213454 | 0.81 | ITGA4 (0.61) | PDCD1CD274ITGA4ITGB7ATM | |
| Hydrochloric Acid SCHEMBL29213451 | 0.81 | ITGA4 (0.61) | PDCD1CD274ITGA4ITGB7ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886219-B | Immunosuppressant, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2023-04-25 | — | — | CN | disclosed |