Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | SNCA | P37840 | 4/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29919467 | 1.00 | APP (0.49) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL30426119 | 0.91 | APP (0.55) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL29395523 | 0.90 | APP (0.49) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL20615236 | 0.90 | APP (0.49) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL30426887 | 0.90 | APP (0.46) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL25426985 | 0.89 | APP (0.47) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL30427232 | 0.89 | APP (0.47) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL30426623 | 0.89 | ALDH1A1 (0.56) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL30427271 | 0.89 | APP (0.48) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL30426288 | 0.89 | APP (0.50) | APPSNCAENPP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230103693-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230103693-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | MKI67, CYP17A1, CYP21A2 | APP 3695/4885SNCA 4834/4885ENPP2 3608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.