SCHEMBL30426288

SCHEMBL30426288

N#C/C(=C\c1cn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ncccc12)C(=O)OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 4/20 0.50
▸ SNCA P37840 4/20 0.50
▸ ENPP2 Q13822 1/20 0.44
▸ ALDH1A1 P00352 3/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ THRB P10828 2/20 0.44
▸ LMNA P02545 1/20 0.41
▸ SLC16A1 P53985 6/20 0.41
▸ ATM Q13315 1/20 0.39
▸ MAPT P10636 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ ELANE P08246 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395523 0.92 APP (0.49) APPSNCAENPP2ALDH1A1KDM4E
SCHEMBL25807306 0.92 APP (0.49) APPSNCAENPP2ALDH1A1KDM4E
SCHEMBL20615236 0.92 APP (0.49) APPSNCAENPP2ALDH1A1KDM4E
SCHEMBL30483269 0.92 APP (0.49) APPSNCAENPP2ALDH1A1KDM4E
SCHEMBL30427271 0.92 APP (0.48) APPSNCAENPP2ALDH1A1KDM4E
SCHEMBL31169579 0.91 APP (0.48) APPSNCAENPP2ALDH1A1KDM4E
SCHEMBL30483276 0.91 APP (0.48) APPSNCAENPP2ALDH1A1KDM4E
SCHEMBL25807334 0.91 APP (0.48) APPSNCAENPP2ALDH1A1KDM4E
SCHEMBL30427033 0.91 APP (0.48) APPSNCAENPP2ALDH1A1KDM4E
SCHEMBL30426119 0.90 APP (0.55) APPSNCAENPP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240327400-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-10-03 — — US disclosed
EP-4172158-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH The Regents of the University of California (US) 2023-05-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240327400-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH PC, FH, PDK1 APP 2860/4885SNCA 4854/4885ENPP2 2354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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