Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | SNCA | P37840 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395523 | 1.00 | APP (0.49) | APPSNCAATMALDH1A1MAPT | |
| SCHEMBL26552311 | 0.96 | APP (0.47) | APPSNCAATMALDH1A1MAPT | |
| SCHEMBL30427271 | 0.94 | APP (0.48) | APPSNCAATMALDH1A1MAPT | |
| SCHEMBL30427343 | 0.94 | APP (0.47) | APPSNCAATMALDH1A1MAPT | |
| SCHEMBL30426569 | 0.93 | APP (0.47) | APPSNCAATMALDH1A1MAPT | |
| SCHEMBL30426288 | 0.92 | APP (0.50) | APPSNCAATMALDH1A1MAPT | |
| SCHEMBL30427033 | 0.92 | APP (0.48) | APPSNCAATMALDH1A1MAPT | |
| SCHEMBL25807306 | 0.92 | APP (0.49) | APPSNCAATMALDH1A1MAPT | |
| SCHEMBL30483269 | 0.92 | APP (0.49) | APPSNCAATMALDH1A1MAPT | |
| SCHEMBL30426119 | 0.91 | APP (0.55) | APPSNCAALDH1A1ENPP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-01-25 | — | — | US | disclosed |
| US-11787804-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-10-17 | — | — | US | disclosed |
| WO-2023130024-A1 | COMPOUNDS FOR TREATMENT OF HAIR LOSS | PELAGE PHARMACEUTICALS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |
| US-20230114220-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-04-13 | — | — | US | disclosed |
| US-20230103693-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-04-06 | — | — | US | disclosed |
| US-20220153738-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-05-19 | — | — | US | disclosed |
| US-11312714-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-26 | — | — | US | disclosed |
| WO-2022006039-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-06 | — | — | WO | disclosed |
| WO-2021127482-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | THE REGENT OF THE UNIVERSITY OFCALIFORNIA (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2020142413-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-09 | — | — | WO | disclosed |
| US-20200157093-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-05-21 | — | — | US | disclosed |
| WO-2019006359-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230114220-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | APP 2641/4885SNCA 4842/4885ATM 2748/4885 |
| US-20200157093-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | APP 2641/4885SNCA 4842/4885ATM 2748/4885 |
| US-11312714-B2 | Compositions and methods for modulating hair growth | PC, FH, SLC25A1 | APP 2641/4885SNCA 4842/4885ATM 2748/4885 |
| US-11787804-B2 | Compositions and methods for modulating hair growth | PC, FH, SLC25A1 | APP 2641/4885SNCA 4842/4885ATM 2748/4885 |
| US-20220153738-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | APP 2641/4885SNCA 4842/4885ATM 2748/4885 |
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | APP 2641/4885SNCA 4842/4885ATM 2748/4885 |
| US-20230103693-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | MKI67, CYP17A1, CYP21A2 | APP 3695/4885SNCA 4834/4885ATM 4415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.