Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3035342 | 0.90 | PGR (0.52) | PGRCYP2C9CYP2D6 | |
| SCHEMBL3029653 | 0.88 | PGR (0.51) | PGRCYP2C9CYP2D6 | |
| SCHEMBL3035642 | 0.88 | PGR (0.66) | PGRCYP2C9CYP2D6 | |
| SCHEMBL3018075 | 0.87 | PGR (0.73) | PGRCYP2C9CYP2D6 | |
| SCHEMBL3027949 | 0.87 | PGR (0.69) | PGRCYP2C9CYP2D6 | |
| SCHEMBL3023699 | 0.87 | PGR (0.58) | PGRCYP2C9CYP2D6 | |
| SCHEMBL3018073 | 0.85 | PGR (0.63) | PGRCYP2C9CYP2D6 | |
| SCHEMBL13218963 | 0.85 | PGR (0.63) | PGRCYP2C9CYP2D6 | |
| SCHEMBL3028436 | 0.84 | PGR (0.65) | PGRCYP2C9CYP2D6 | |
| SCHEMBL3035611 | 0.84 | PGR (0.69) | PGRCYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216813-A1 | PYRROLIDINEANILINES | SMITHKLINE BEECHAM CORPORATION | 2010-08-26 | — | — | US | disclosed |
| US-20100216813-A1 | PYRROLIDINEANILINES | SMITHKLINE BEECHAM CORPORATION | 2010-08-26 | — | — | US | disclosed |
| US-20100216813-A1 | PYRROLIDINEANILINES | SMITHKLINE BEECHAM CORPORATION | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216813-A1 | PYRROLIDINEANILINES | PGF, ARG1, CYP19A1 | PGR 11/4885CYP2C9 2288/4885CYP2D6 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.