Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | NMBR | P28336 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439119 | 1.00 | ITGB3 (0.45) | ITGB3ITGA2BSYKPPARAACE | |
| SCHEMBL17596477 | 1.00 | ITGB3 (0.45) | ITGB3ITGA2BSYKPPARAACE | |
| SCHEMBL25240561 | 0.94 | TACR1 (0.47) | SYKNMBRCTSKCTSLCTSB | |
| SCHEMBL19340443 | 0.94 | TACR1 (0.47) | SYKNMBRCTSKCTSLCTSB | |
| SCHEMBL30002314 | 0.94 | TACR1 (0.47) | SYKNMBRCTSKCTSLCTSB | |
| SCHEMBL16100108 | 0.90 | CTSS (0.48) | PPARAACECTSKCTSLCTSS | |
| SCHEMBL31407630 | 0.90 | CTSS (0.48) | PPARAACECTSKCTSLCTSS | |
| SCHEMBL16100109 | 0.90 | CTSS (0.48) | PPARAACECTSKCTSLCTSS | |
| SCHEMBL19410161 | 0.89 | PLA2G2A (0.47) | ITGB3ITGA2BPPARAACE | |
| SCHEMBL19410159 | 0.89 | PLA2G2A (0.47) | ITGB3ITGA2BPPARAACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370530-A1 | MACROCYCLIC IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023288213-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-19 | — | — | WO | disclosed |