Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22659096 | 0.85 | MCL1 (0.52) | HTTALOX15PLK1ALDH1A1NPC1 | |
| SCHEMBL30616281 | 0.81 | ALOX15 (0.64) | HTTALOX15PLK1ALDH1A1NPC1 | |
| SCHEMBL21218118 | 0.81 | PLK1 (0.64) | HTTALOX15PLK1ALDH1A1NPC1 | |
| SCHEMBL22659328 | 0.81 | ALOX15 (0.64) | HTTALOX15PLK1ALDH1A1NPC1 | |
| SCHEMBL22680033 | 0.81 | CASP6 (0.54) | PARP1HTTALOX15PLK1AR | |
| SCHEMBL30152477 | 0.80 | PDGFRB (0.64) | PARP1HTTALOX15ALDH1A1MKNK1 | |
| SCHEMBL30229311 | 0.80 | PDGFRB (0.64) | PARP1HTTALOX15ALDH1A1MKNK1 | |
| SCHEMBL28839474 | 0.80 | PDGFRB (0.64) | PARP1HTTALOX15ALDH1A1MKNK1 | |
| SCHEMBL23660925 | 0.79 | MCL1 (0.52) | HTTALOX15PLK1ALDH1A1NPC1 | |
| SCHEMBL29548145 | 0.79 | PARP1 (0.51) | PARP1HTTALOX15PLK1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |