Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.50 |
| ▸ | TRPC5 | Q9UL62 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PARG | Q86W56 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23997444 | 1.00 | GRIN1 (0.51) | GRIN1GRIN2BPCSK9TRPC5NPC1 | |
| SCHEMBL25720289 | 0.90 | NPC1 (0.46) | GRIN1GRIN2BPCSK9TRPC5NPC1 | |
| SCHEMBL9977495 | 0.76 | MEN1 (0.47) | ALDH1A1TSHRFEN1CHRM5KMT2A | |
| SCHEMBL23997178 | 0.75 | OPRM1 (0.51) | GRIN1GRIN2BPCSK9OPRM1FEN1 | |
| SCHEMBL24405792 | 0.73 | ALDH1A1 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL25719543 | 0.73 | ALDH1A1 (0.50) | NPC1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL25718704 | 0.72 | MIF (0.62) | ALDH1A1TSHRPARGKMT2AMEN1 | |
| SCHEMBL24852025 | 0.72 | MPO (0.45) | PCSK9TRPC5OPRM1CHRM5KMT2A | |
| SCHEMBL31192223 | 0.72 | MPO (0.45) | PCSK9TRPC5OPRM1CHRM5KMT2A | |
| SCHEMBL25719533 | 0.72 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115836054-B | IL4I1 inhibitors and methods of use | 默沙东有限责任公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-115836054-A | IL4I1 inhibitors and methods of use | 默沙东有限责任公司 | 2023-03-21 | — | — | CN | disclosed |