Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3009943 | 0.98 | TSHR (0.51) | TSHRGPR35ALDH1A1TP53HPGD | |
| Water SCHEMBL3012137 | 0.97 | TSHR (0.50) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL8012475 | 0.86 | GAA (0.56) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL3009938 | 0.86 | GPR35 (0.53) | TSHRGPR35ALDH1A1TP53HPGD | |
| Water SCHEMBL3012136 | 0.85 | GPR35 (0.51) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL19742607 | 0.85 | GAA (0.54) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL7808995 | 0.85 | GPR35 (0.51) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL11308302 | 0.83 | GAA (0.51) | TSHRGPR35ALDH1A1GAATHRB | |
| SCHEMBL51277 | 0.82 | GPR35 (0.60) | TSHRGPR35ALDH1A1TP53HPGD | |
| SCHEMBL25252499 | 0.81 | CYP1A2 (0.44) | TSHRGPR35ALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100209953-A1 | METHOD OF DETERMINING CARBONIC ANHYDRASE I ACTIVITY | YAMASA CORPORATION (JP) | 2010-08-19 | — | — | US | claimed |
| US-20100209953-A1 | METHOD OF DETERMINING CARBONIC ANHYDRASE I ACTIVITY | YAMASA CORPORATION (JP) | 2010-08-19 | — | — | US | disclosed |
| US-20100209953-A1 | METHOD OF DETERMINING CARBONIC ANHYDRASE I ACTIVITY | YAMASA CORPORATION (JP) | 2010-08-19 | — | — | US | disclosed |
| US-20070196885-A1 | Method of determining carbonic anhydrase i activity | YAMASA CORPORATION (JP) | 2007-08-23 | — | — | US | disclosed |
| EP-1734132-A1 | METHOD OF DETERMINING CARBONIC ANHYDRASE I ACTIVITY | YAMASA CORPORATION (JP) | 2006-12-20 | — | — | EP | disclosed |