SCHEMBL51277

SCHEMBL51277

O=[N+]([O-])c1ccc(O)c(Cc2cc([N+](=O)[O-])ccc2O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.60
ALDH1A1 P00352 2/20 0.60
TSHR P16473 2/20 0.60
HPGD P15428 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
TP53 P04637 1/20 0.60
MAPK1 P28482 1/20 0.60
GAA P10253 1/20 0.58
THRB P10828 1/20 0.58
CTSB P07858 1/20 0.56
ERN1 O75460 1/20 0.55
NOX4 Q9NPH5 1/20 0.51
SNCA P37840 1/20 0.50
APP P05067 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HSP90AA1 P07900 2/20 0.47
ALOX15 P16050 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CRHBP P24387 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19501412 0.93 GPR35 (0.53) GPR35ALDH1A1TSHRHPGDSMN1; SMN2
SCHEMBL4231830 0.86 ALDH1A1 (0.58) GPR35ALDH1A1TSHRHPGDSMN1; SMN2
SCHEMBL216753 0.86 GPR35 (0.58) GPR35ALDH1A1TSHRHPGDSMN1; SMN2
SCHEMBL786831 0.85 ALDH1A1 (0.56) GPR35ALDH1A1TSHRHPGDSMN1; SMN2
SCHEMBL360284 0.85 TSHR (0.56) GPR35ALDH1A1TSHRHPGDSMN1; SMN2
Hydrochloric Acid SCHEMBL22773531 0.85 GPR35 (0.56) GPR35ALDH1A1TSHRHPGDSMN1; SMN2
SCHEMBL131912 0.85 GPR35 (0.56) GPR35ALDH1A1TSHRHPGDSMN1; SMN2
SCHEMBL786832 0.85 GAA (0.59) GPR35ALDH1A1TSHRHPGDSMN1; SMN2
SCHEMBL15283303 0.85 ALDH1A1 (0.56) GPR35ALDH1A1TSHRHPGDSMN1; SMN2
SCHEMBL13827067 0.85 GPR35 (0.56) GPR35ALDH1A1TSHRHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9348252-B2 Image forming apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2016-05-24 US disclosed
US-9348252-B2 Image forming apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2016-05-24 US disclosed
US-20160011537-A1 Image Forming Apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2016-01-14 US disclosed
US-20160011537-A1 Image Forming Apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2016-01-14 US disclosed
EP-2181853-B1 Thermosensitive recording medium JUJO PAPER CO LTD (JP) 2015-09-23 EP disclosed
US-8933208-B2 Photo-responsive liquid crystalline compound and its applications NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2015-01-13 US disclosed
US-8933208-B2 Photo-responsive liquid crystalline compound and its applications NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2015-01-13 US disclosed
US-8492308-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-07-23 US disclosed
US-20130066068-A1 PHOTO-RESPONSIVE LIQUID CRYSTALLINE COMPOUND AND ITS APPLICATIONS NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2013-03-14 US disclosed
US-20130066068-A1 PHOTO-RESPONSIVE LIQUID CRYSTALLINE COMPOUND AND ITS APPLICATIONS NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2013-03-14 US disclosed
EP-2112001-B1 THERMOSENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2011-05-11 EP disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-2261045-A1 HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2010-12-15 EP disclosed
EP-2181853-A1 THERMAL RECORDING MATERIAL Nippon Paper Industries Co., Ltd. (JP) 2010-05-05 EP disclosed
US-20100099557-A1 Thermosensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-04-22 US disclosed
US-7141359-B2 Developers for thermal recording materials and thermal recording materials API CORPORATION (JP) 2006-11-28 US disclosed
US-20050118526-A1 Developers for thermal recording materials and thermal recording materials MITSUBISHI CHEMICAL CORPORATION (JP) 2005-06-02 US disclosed
EP-1393923-A1 DEVELOPERS FOR THERMAL RECORDING MATERIALS AND THERMAL RECORDING MATERIALS API Corporation (JP) 2004-03-03 EP disclosed
EP-0239157-B1 POLYMER MIXTURE WHICH COMPRISES AN AROMATIC POLYCARBONATE, A POLYBUTYLENE TEREPHTALATE AND AN AGENT TO IMPROVE THE IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1991-01-02 EP disclosed
WO-1987005920-A1 POLYMER MIXTURE WHICH COMPRISES AN AROMATIC POLYCARBONATE, A POLYALKYLENE TEREPHTHALATE AND AN AGENT TO IMPROVE THE IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1987-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130066068-A1 PHOTO-RESPONSIVE LIQUID CRYSTALLINE COMPOUND AND ITS APPLICATIONS CRY1, CRY2, CRYAA GPR35 1700/4885ALDH1A1 2525/4885TSHR 2939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.