Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 2/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30349474 | 0.91 | TYK2 (0.50) | ADORA3ADORA2AADORA1CDK2TYK2 | |
| SCHEMBL30349558 | 0.86 | TYK2 (0.61) | TYK2STAT3MAPTSMN1; SMN2USP2 | |
| SCHEMBL21811191 | 0.86 | TYK2 (0.61) | TYK2STAT3MAPTSMN1; SMN2USP2 | |
| SCHEMBL21887777 | 0.84 | MAPT (0.44) | ADORA3ADORA2AADORA2BADORA1CCNA2 | |
| SCHEMBL30378065 | 0.83 | TYK2 (0.50) | ADORA3ADORA2AADORA2BADORA1CCNA2 | |
| SCHEMBL30349310 | 0.83 | CCNA2 (0.54) | ADORA3ADORA2AADORA2BADORA1CCNA2 | |
| SCHEMBL30349442 | 0.80 | TYK2 (0.77) | TYK2STAT3 | |
| SCHEMBL21887781 | 0.79 | NPSR1 (0.43) | ADORA3ADORA2AADORA2BADORA1GAA | |
| SCHEMBL21887788 | 0.79 | TYK2 (0.53) | TYK2STAT3SMN1; SMN2ALOX15TSHR | |
| SCHEMBL30377589 | 0.78 | POLB (0.51) | ADORA3ADORA2AADORA1CDK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638915-B | Pyrazolo [1,5-a ] pyrimidine-3-carboxamide derivatives for the treatment of psoriasis and systemic lupus erythematosus | 伊莱利利公司 | 2023-04-07 | — | — | CN | disclosed |