Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 4/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CDK7 | P50613 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30349340 | 0.91 | ADORA3 (0.48) | TYK2STAT3MAPTMEN1KMT2A | |
| SCHEMBL30377589 | 0.85 | POLB (0.51) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL21887328 | 0.83 | TYK2 (0.66) | TYK2STAT3PDE4D | |
| SCHEMBL30349442 | 0.83 | TYK2 (0.77) | TYK2STAT3PDE4D | |
| SCHEMBL21811164 | 0.82 | AKR1C3 (0.46) | TYK2STAT3MAPTMEN1KMT2A | |
| SCHEMBL30378401 | 0.82 | TYK2 (0.53) | TYK2STAT3MAPTPOLBKDM4E | |
| SCHEMBL21887378 | 0.76 | KCNH2 (0.44) | TYK2STAT3MAPTMEN1KMT2A | |
| SCHEMBL21887349 | 0.76 | TYK2 (0.69) | TYK2STAT3PDE4D | |
| SCHEMBL21811202 | 0.75 | TYK2 (0.60) | TYK2STAT3MAPTMEN1KMT2A | |
| SCHEMBL30349550 | 0.75 | TYK2 (0.60) | TYK2STAT3MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638915-B | Pyrazolo [1,5-a ] pyrimidine-3-carboxamide derivatives for the treatment of psoriasis and systemic lupus erythematosus | 伊莱利利公司 | 2023-04-07 | — | — | CN | disclosed |