Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ASPH | Q12797 | 2/20 | 0.43 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.43 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CD38 | P28907 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30349474 | 0.85 | TYK2 (0.50) | POLBADORA3ADORA2AADORA1MEN1 | |
| SCHEMBL30377819 | 0.83 | TYK2 (0.62) | POLB | |
| SCHEMBL22092692 | 0.82 | POLB (0.44) | POLBADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL30378401 | 0.80 | TYK2 (0.53) | POLBADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL30349340 | 0.78 | ADORA3 (0.48) | POLBADORA3ADORA2AADORA1MEN1 | |
| SCHEMBL24987471 | 0.75 | POLB (0.46) | POLBKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL22092637 | 0.75 | KDM4E (0.41) | POLBADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL30378065 | 0.73 | TYK2 (0.50) | POLBADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL30349310 | 0.73 | CCNA2 (0.54) | POLBADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL22103738 | 0.73 | TYK2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166163-B | 7- (methylamino) pyrazolo [1,5-A ] pyrimidine-3-carboxamide derivatives | 伊莱利利公司 | 2023-04-07 | — | — | CN | disclosed |