Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26090376 | 1.00 | CACNA1H (0.36) | CACNA1HDDB1CRBNMAP2K1POLB | |
| SCHEMBL26436052 | 0.86 | POLB (0.33) | POLBFPR1FPR2 | |
| SCHEMBL26435659 | 0.86 | FPR2 (0.39) | POLBFPR1FPR2 | |
| SCHEMBL26090446 | 0.86 | FPR2 (0.39) | POLBFPR1FPR2 | |
| SCHEMBL26090625 | 0.85 | DDB1 (0.36) | DDB1CRBNMAP2K1POLBMEN1 | |
| SCHEMBL30349632 | 0.85 | DDB1 (0.36) | DDB1CRBNMAP2K1POLBMEN1 | |
| SCHEMBL26089566 | 0.83 | LMNA (0.40) | DDB1CRBNMEN1KMT2A | |
| SCHEMBL26088923 | 0.82 | PRMT5 (0.40) | DDB1CRBN | |
| SCHEMBL30349564 | 0.81 | SIGMAR1 (0.33) | CRBNPOLBFPR1FPR2 | |
| SCHEMBL26515041 | 0.81 | SIGMAR1 (0.33) | CRBNPOLBFPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069731-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |