Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 4/20 | 0.52 |
| ▸ | RXRB | P28702 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1254744 | 1.00 | RAB9A (0.68) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL1255787 | 0.87 | NPC1 (0.55) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL19511328 | 0.84 | MAOB (0.63) | RAB9ASMN1; SMN2NPC1POLBMAPT | |
| SCHEMBL1221922 | 0.83 | MAPT (0.63) | PLA2G4BMAPTALKBH1L3MBTL1FFAR1 | |
| SCHEMBL12076388 | 0.82 | RAB9A (0.68) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL6871510 | 0.82 | NR4A2 (0.63) | MAPTALKBH1L3MBTL1MRGPRX4KDM5A | |
| SCHEMBL1186510 | 0.82 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL28335896 | 0.82 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL7230242 | 0.81 | MAPT (0.56) | MAPTRXRARXRBL3MBTL1MRGPRX4 | |
| SCHEMBL3416184 | 0.80 | CALM1 (0.50) | RAB9ASMN1; SMN2NPC1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567443-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-28 | — | — | CN | disclosed |
| CN-115925679-A | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-07 | — | — | CN | disclosed |