Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.54 |
| ▸ | PDE2A | O00408 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1257063 | 0.87 | KDM4C (0.63) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL30350651 | 0.87 | KDM4C (0.63) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL16727048 | 0.84 | RAB9A (0.55) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL1254744 | 0.82 | RAB9A (0.68) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL30350652 | 0.82 | RAB9A (0.68) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL12076214 | 0.82 | MEN1 (0.67) | SMN1; SMN2PLA2G4BMRGPRX4KDM5AKDM4C | |
| SCHEMBL30046491 | 0.82 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL1186510 | 0.81 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL28335896 | 0.81 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL9356270 | 0.81 | RAB9A (0.66) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2495243-B1 | NOVEL 5-FLUOROURACIL DERIVATIVE | DELTA-FLY PHARMA INC (JP) | 2016-12-28 | — | — | EP | disclosed |
| US-8889699-B2 | 5-fluorouracil derivative | DELTA-FLY PHARMA, INC. (JP) | 2014-11-18 | — | — | US | disclosed |
| US-20120232103-A1 | NOVEL 5-FLUOROURACIL DERIVATIVE | DELTA-FLY PHARMA, INC. (JP) | 2012-09-13 | — | — | US | disclosed |
| EP-2495243-A1 | NOVEL 5-FLUOROURACIL DERIVATIVE | Delta-Fly Pharma, Inc. (JP) | 2012-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232103-A1 | NOVEL 5-FLUOROURACIL DERIVATIVE | DPYD, FAU, MTHFD1 | RAB9A 1813/4885SMN1; SMN2 3155/4885NPC1 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.